Thirty years of saying NO: sources, fate, actions, and misfortunes of the endothelium-derived vasodilator mediator

PM Vanhoutte, Y Zhao, A Xu, SWS Leung - Circulation research, 2016 - Am Heart Assoc
… of this article), NO is a powerful vasodilator that prevents or reduces vasoconstrictions. …
Because activation of vascular β-adrenoceptors causes vasodilatation, an increased production …

Communication is key: mechanisms of intercellular signaling in vasodilation

JK Freed, DD Gutterman - Journal of cardiovascular …, 2017 - journals.lww.com
Thirty years later, we now understand that multiple endothelial-derived vasodilatory
For instance, it has been shown that the mediator of ACh-induced vasodilation transitions …

Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans

P Smits, SB Williams, DE Lipson, P Banitt, GA Rongen… - Circulation, 1995 - Am Heart Assoc
vasodilator effect of adenosine was thought to be based on direct stimulation of A 2 -adenosine
receptors on vascular smooth muscle cells, which mediate an … -independent vasodilation. …

Vasodilator therapy

WW Parmley, K Chatterjee - Current problems in cardiology, 1978 - Elsevier
… Further studies are required, however, to put this mechanism in final perspective with
regard to its importance as a mediator of some of the hemodynamic effects of the vasodilators. …

The discovery of nitric oxide as the endogenous nitrovasodilator.

S Moncada, RM Palmer, EA Higgs - Hypertension, 1988 - Am Heart Assoc
… that mediates the relaxation induced by some vasodilators, including acetylchollne and
bradykinin. … to the list of mediators that regulate vascular reactivity. In the last 2 years it has been …

[PDF][PDF] Bradykinin-an undervalued mediator

K Belowska-Bień, E Szeląg, J Szeląg… - Post N Med, 2017 - pnmedycznych.pl
Vasodilating properties of bradykinin that manifest as tissue … Bradykinin is one of endogenous
mediators with vasodilating … with PI3K/Akt/eNOS mediators followed by secretion of NO. …

[图书][B] Studies on the afferent mechanisms and the neurohumoral mediation of active reflex dilatation

MJ Brody - 1961 - search.proquest.com
… The above conflicti ng references about the mediator of anti dromic vasodilatation are
conspicuous because of their absence of carefully controlled experiments, and because of species …

[PDF][PDF] Three decades of endothelium research

AJ Flammer, TF Lüscher - Swiss medical weekly, 2010 - smw.ch
Thirty years ago, Furchgott and Zawadzki demonstrated that … vasodilatation in the presence
of reduced NO availability [30]. Studies have identified several molecules or mediators that …

Relative contribution of vasodilator prostanoids, NO, and KATP channels to human forearm metabolic vasodilation

HMO Farouque, IT Meredith - American Journal of …, 2003 - journals.physiology.org
… The endothelium is able to release a number of paracrine vasodilator factors, such as NO
and prostacyclin. The release of these mediators may be stimulated by forces exerted by …

Regulation of vascular reactivity by established and emerging GPCRs

JJ Maguire, AP Davenport - Trends in pharmacological sciences, 2005 - cell.com
… Figure 2GPCRs that mediate direct or indirect vasodilatation. … ’ to Ca 2+ , and subsequent
vasodilatation. A large number of … to vascular smooth muscle vasodilatation. The key indicates …