… , involved in the regulation of the VEGF family expression and significant effects on receptor-…
, the VEGF/VEGFR’s regulation is a complex multifaceted signalling web, with many VEGF/…

… perspectives and targets presented by the VEGF family predict their ability … treating
cardiovascular diseases. Until now, no relevant review about the biological effects of the VEGF family …

… The level of VEGF expression also correlates with … VEGF in tumor angiogenesis and the
correlation with tumor growth, VEGF has emerged as the most promising therapeutic target …

… All of the mAbs discussed in this review target the VEGF pathway; however the specificity
of the different mAbs affects the function of these therapies within the tumor microenvironment …

… of VEGF/VEGFR are correlated with the treatment, relapse and prognosis of hematolymphoid
tumors. In order for VEGF family and their receptors as antiangiogenic targets to treat solid …

… factor (PDGF) family of molecules is structurally related to the VEGF family and has been …
target VEGF function are currently in development, including those targeting VEGF (eg, VEGF …

… The VEGF family of genes contains at least 7 members, including the viral … VEGF-E, whereas
the VEGFR family of genes has 3 to 4 members depending on the vertebrate species. VEGF…

… receptor subunits can transphosphorylate each other as an essential first step of VEGF-induced
intracellular signaling and potential target for antiangiogenic therapy.[9] [10] …

… Hence, several different strategies have been designed to target VEGF signal transduction.
In the last decades, multiple inhibitors have been therapeutically validated in preclinical …

… of targets for antidepressant treatments. We recently characterized a role for vascular
endothelial growth factor (VEGF) in cellular and behavioral antidepressant responses. VEGF is a …