Inflammation in deep vein thrombosis: a therapeutic target?
… -thrombotic syndrome. Here, we review the link between inflammation and deep vein thrombosis
… the treatment of deep vein thrombosis and the prevention of post-thrombotic syndrome. …
… the treatment of deep vein thrombosis and the prevention of post-thrombotic syndrome. …
Therapeutic strategies for thrombosis: new targets and approaches
N Mackman, W Bergmeier, GA Stouffer… - Nature reviews Drug …, 2020 - nature.com
… most often in the legs or arms, a process known as deep vein thrombosis 10 . These clots …
as pulmonary embolism (PE). Deep vein thrombosis and PE are collectively known as venous …
as pulmonary embolism (PE). Deep vein thrombosis and PE are collectively known as venous …
Factor XI as a therapeutic target
… Results of a recent trial comparing antisense-induced factor XI reduction to standard-dose
low molecular–weight heparin as prophylaxis for venous thrombosis during knee replacement …
low molecular–weight heparin as prophylaxis for venous thrombosis during knee replacement …
[HTML][HTML] SLC44A2–A novel therapeutic target for venous thrombosis?
A Constantinescu‐Bercu, II Salles‐Crawley… - Journal of Thrombosis …, 2020 - jthjournal.org
… also identify potential (adjunctive) therapeutic targets for thromboprophylaxis that do not
modify bleeding risk. In this issue of the Journal of Thrombosis and Haemostasis, Tilburg et al …
modify bleeding risk. In this issue of the Journal of Thrombosis and Haemostasis, Tilburg et al …
[HTML][HTML] Thrombosis and vascular inflammation in diabetes: mechanisms and potential therapeutic targets
N Pechlivani, RA Ajjan - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
… FXII and prekallikrein have been demonstrated in vivo using FeCl3- induced and stenosis-induced
models of venous thrombosis (114). Different approaches, such as the use of …
models of venous thrombosis (114). Different approaches, such as the use of …
Venous thrombosis
… vein thrombosis is associated with an increased risk of VTE for more than 5 years after the
thrombotic … currently in clinical use are enzyme-specific and target either factor Xa or thrombin (…
thrombotic … currently in clinical use are enzyme-specific and target either factor Xa or thrombin (…
Triggers, targets and treatments for thrombosis
N Mackman - Nature, 2008 - nature.com
… thrombosis is treated with drugs that target platelets, and venous thrombosis is treated with
drugs that target … makes it difficult to identify therapeutic targets. An exception seems to be the …
drugs that target … makes it difficult to identify therapeutic targets. An exception seems to be the …
Platelet signaling and disease: targeted therapy for thrombosis and other related diseases
J Yeung, W Li, M Holinstat - Pharmacological reviews, 2018 - ASPET
… therapies targeted to the platelet. Additionally, we highlight the promising receptor and enzymatic
targets … The pathophysiological mechanisms of arterial and venous thrombus formation …
targets … The pathophysiological mechanisms of arterial and venous thrombus formation …
Factor XII as a therapeutic target in thromboembolic and inflammatory diseases
KF Nickel, AT Long, TA Fuchs, LM Butler… - … , thrombosis, and …, 2017 - Am Heart Assoc
… to arterial thrombosis and contributes to venous thromboembolism. Mouse models have
shown a critical role of FXII in deep vein thrombosis. Stasis-driven deep vein thrombosis in the …
shown a critical role of FXII in deep vein thrombosis. Stasis-driven deep vein thrombosis in the …
Pathophysiology of deep vein thrombosis
S Navarrete, C Solar, R Tapia, J Pereira… - Clinical and …, 2023 - Springer
… Deep venous thrombosis is a frequent, multifactorial disease … Most of the time deep venous
thrombosis is triggered by the … thrombosis and therefore can be used as a therapeutic target…
thrombosis is triggered by the … thrombosis and therefore can be used as a therapeutic target…
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