Mechanisms of breathing instability in patients with obstructive sleep apnea

M Younes, M Ostrowski, R Atkar… - Journal of Applied …, 2007 - journals.physiology.org
ventilatory instability is fairly simple; obstruction continues until arousal occurs and recurs on
resumption of sleep… Instability of ventilatory control in patients with obstructive sleep apnea. …

Obstructive sleep apnea complicating negative-pressure ventilatory support in patients with chronic paralytic/restrictive ventilatory dysfunction

JR Bach, J Penek - Chest, 1991 - Elsevier
… We observed in at least seven patients that respiratory control centers … ventilatory aid during
daytime hours as well as overnight. The normalization of Pco 2 by adequate ventilation even …

Ventilatory pattern at rest and response to hypercapnic stimulation in patients with obstructive sleep apnea syndrome

E Benlloch, P Cordero, P Morales, JJ Soler, V Macian - Respiration, 1995 - karger.com
… syndrome and phenomena which lead to upper airway obstruction are only partially …
ventilatory control have been considered to have important implications in obstructive sleep apnea

Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy

DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
… dilator muscle control and function during sleep, increased propensity for awakening during
airway narrowing (low respiratory arousal threshold) and respiratory control instability (high …

What is central sleep apnea?

A Malhotra, RL Owens - Respiratory care, 2010 - rc.rcjournal.com
… Central sleep apnea (CSA) describes a group of conditions in which cessations in air flow …
respiratory effort. In contrast, obstructive sleep apnea patients have ongoing respiratory effort …

Ventilatory burden as a measure of obstructive sleep apnea severity is predictive of cardiovascular and all-cause mortality

A Parekh, K Kam, S Wickramaratne… - … Journal of Respiratory …, 2023 - atsjournals.org
Obstructive sleep apnea (OSA) is a common chronic condition affecting more than 1 billion …
apnea–hypopnea index (AHI), which is the frequency of respiratory events defined by apneas

The heterogeneity of obstructive sleep apnea (predominant obstructive vs pure obstructive apnea)

A Xie, A Bedekar, JB Skatrud, M Teodorescu, Y Gong… - Sleep, 2011 - academic.oup.com
… We quantified the propensity for respiratory control instability and sleep apnea by measuring
CO 2 reserve (ie, the difference in PCO 2 between eupnea and the apneic threshold). With …

Adult obstructive sleep apnea: pathophysiology and diagnosis

SP Patil, H Schneider, AR Schwartz, PL Smith - Chest, 2007 - Elsevier
Ventilatory control mechanisms may also play a role in modulating pharyngeal collapsibility
during sleep… 65 Increased hypercapnic ventilatory responses, prolonged circulatory times, or …

[HTML][HTML] Altered ventilatory responses to exercise testing in young adult men with obstructive sleep apnea

TA Hargens, SG Guill, A Aron, D Zedalis, JM Gregg… - Respiratory …, 2009 - Elsevier
… an exaggerated ventilatory response to exercise … ventilatory responses at submaximal and
maximal exercise intensities. Therefore, the purpose of this study is to evaluate the ventilatory

Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea

BA Edwards, DJ Eckert, DG McSharry… - … journal of respiratory …, 2014 - atsjournals.org
… with obstructive sleep apnea with a low respiratory … of obstructive sleep apnea so that
treatments can be directed according to the underlying pathophysiology. Obstructive sleep apnea (…