Myocardial fibrosis and pathologic hypertrophy in the rat with renovascular hypertension

KT Weber, JS Janicki, R Pick, J Capasso… - The American journal of …, 1990 - Elsevier
fibrosis occurs in the hyperbophied left ventricle of the rat with … consequences of this fibrosis
and the mechanisms invotved … considered as contributing to overall ventricular hypertrophy. …

Myocardial fibrosis and stiffness with hypertrophy and heart failure in the spontaneously hypertensive rat

CH Conrad, WW Brooks, JA Hayes, S Sen… - Circulation, 1995 - Am Heart Assoc
… function, and fibrosis in the spontaneously hypertensive rat (SHR), a … cardiac function follows
a long period of stable hypertrophy. … to be increased in cardiac hypertrophy, and it has been …

Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart

K Yamamoto, T Masuyama, Y Sakata… - Cardiovascular …, 2002 - academic.oup.com
cardiac disorder. This study investigated differential contribution of left ventricular (LV)
hypertrophy and fibrosis … Methods: Dahl-Iwai salt-sensitive rats fed on high-salt diet since 7 weeks …

Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway

Y Zhang, L Shao, A Ma, G Guan, J Wang… - Hypertension …, 2014 - nature.com
… TEL alleviated myocardial fibrosis in hypertensive left ventricular hypertrophic rats The
degree of myocardial fibrosis in the hypertensive left ventricular hypertrophic rats could be …

… HORMONE ATTENUATES MYOCARDIAL FIBROSIS IN RATS WITH CHRONIC PRESSURE OVERLOAD‐INDUCED LEFT VENTRICULAR HYPERTROPHY

VO Moreira, CA Pereira, MO Silva… - Clinical and …, 2009 - Wiley Online Library
… persistent pressure overload-induced left ventricular hypertrophy has not been defined. …
ventricular function and remodelling in rats with chronic pressure overload-induced hypertrophy

Reactive and reparative myocardial fibrosis in arterial hypertension in the rat

CG Brilla, KT Weber - Cardiovascular research, 1992 - academic.oup.com
fibrosis and scarring in either model irrespective of the development of left ventricular
hypertrophy and … prevented hypertension and left ventricular hypertrophy, but not scarring. These …

Cardiac and vascular fibrosis and hypertrophy in aldosterone-infused rats: role of endothelin-1

JB Park, EL Schiffrin - American journal of hypertension, 2002 - academic.oup.com
… of cardiac fibrosis and left ventricular hypertrophy … for BP elevation, cardiac fibrosis occurs
in both ventricles, whereas atrial … the left but not the right ventricle. Furthermore, prevention of …

Pathologic hypertrophy with fibrosis: the structural basis for myocardial failure

KT Weber, CG Brilla, SE Campbell, G Zhou… - Blood …, 1992 - Taylor & Francis
rat [ 131. Myocardial hydroxyproline concentration was found to remain normal despite
ventricular hypertrophy. … Reactive and reparative fibrosis in the hypertrophied rat left ventricle: two …

Angiotensin II–induced cardiomyocyte hypertrophy and cardiac fibrosis in stroke-prone spontaneously hypertensive rats

Y Ikeda, T Nakamura, H Takano, H Kimura… - Journal of Laboratory …, 2000 - Elsevier
… regression of hypertensive left ventricular hypertrophy (LVH) by … stroke-prone spontaneously
hypertensive rats (SHRSPs). Male … (SBP), left ventricular weight (LVW), left ventricular (LV) …

Left ventricular hypertrophy: a new approach for fibrosis inhibition

ML Muiesan - Journal of Hypertension, 2002 - journals.lww.com
… in non-failing hypertrophy after abdominal aortic coartation [ … the development of cardiac
hypertrophy and fibrosis may vary … and perivascular fibrosis in the hypertensive Ren2 rats [ 11 ]. …