WNT–β-catenin signalling—a versatile player in kidney injury and repair

SJ Schunk, J Floege, D Fliser, T Speer - Nature Reviews Nephrology, 2021 - nature.com
… The WNT–β-catenin system is an evolutionary conserved … β-catenin activation stimulates
tissue regeneration after acute kidney injury, whereas sustained (uncontrolled) WNT–β-catenin

[HTML][HTML] Wnt/β-catenin signaling pathway-a versatile player in apoptosis and autophagy

Q Ma, J Yu, X Zhang, X Wu, G Deng - Biochimie, 2023 - Elsevier
… role of the Wnt/β-catenin signaling pathway in apoptosis and … the regulation of Wnt/β-catenin
is generally positive. However… Wnt/β-catenin and apoptosis; b) Wnt/β-catenin influences the …

Wnt/β-catenin signaling: new (and old) players and new insights

H Huang, X He - Current opinion in cell biology, 2008 - Elsevier
… Therefore the study of Wnt/β-catenin signaling not only helps to … of β-catenin degradation
complex and Wnt receptor activation. For a more comprehensive discussion on Wnt/β-catenin

The many faces and functions of βcatenin

T Valenta, G Hausmann, K Basler - The EMBO journal, 2012 - embopress.org
βcatenin. The result is a very broad and informative picture of this evolutionary‐conserved,
versatile … two types according to the role played by βcatenin. In the canonical Wnt cascade, …

Targeting the versatile Wnt/β-catenin pathway in cancer biology and therapeutics: from concept to actionable strategy

K Dzobo, NE Thomford… - Omics: a journal of …, 2019 - liebertpub.com
… /β-catenin signaling displays varied and highly versatile biological functions in animals, with
virtually all tissues requiring the Wnt/β-catenin … the Wnt/β-catenin is the role played by the …

βcatenin signaling and cancer

PJ Morin - Bioessays, 1999 - Wiley Online Library
… ß-catenin has emerged as an important player in a number of human neoplasias. Although
ß-catenin … will focus on the oncogenic properties of ß-catenin signaling in human cancer. ß-…

How do they do Wnt they do?: regulation of transcription by the Wnt/βcatenin pathway

HC Archbold, YX Yang, L Chen… - Acta …, 2012 - Wiley Online Library
… Wnt/βcatenin signalling is known to play many roles in … on how Wnt/βcatenin signalling
regulates gene expression in a … a large portion of Wnt/βcatenin signalling, will be discussed in …

Beta-catenin versus the other armadillo catenins: assessing our current view of canonical Wnt signaling

RK Miller, JY Hong, WA Muñoz, PD McCrea - Progress in molecular …, 2013 - Elsevier
… This is understandable because beta-catenin is the dominant player, with its loss or gain
often resulting in graphic phenotypic and molecular effects. When manipulating members of the …

βcatenin as a potential key target for tumor suppression

Y Fu, S Zheng, N An, T Athanasopoulos… - … journal of cancer, 2011 - Wiley Online Library
played an essential role in stabilizing cadherin-catenin … of β-catenin in cadherin junction
is versatile. Besides functions as a bridge in cadherin/β-catenin/α-catenin complex, β-catenin is …

[HTML][HTML] Curbing the nuclear activities of βcatenin

A Hecht, R Kemler - EMBO reports, 2000 - embopress.org
… factors can sequester βcatenin from TCFs while others synergize with βcatenin–TCF …
that makes βcatenin so hard to understand is what also endows it with such versatility in …