CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis

AG Thompson, E Gray, I Mäger, ML Thézénas… - Clinical Proteomics, 2020 - Springer
Proteomic analysis of CSF EVs in ALS detects intracellular alterations in protein homeostatic
mechanisms, previously only identified in pathological tissues. This supports the wider use …

[HTML][HTML] Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress

G Vasam, R Nadeau, VJJ Cadete… - The FASEB …, 2021 - ncbi.nlm.nih.gov
vesicles, which may indicate mitochondrial stress. In conclusion, our study provides an MDV
proteomics … iron‐sulfur cluster binding proteins and proteins involved in redox homeostasis / …

A perspective on extracellular vesicles proteomics

L Rosa-Fernandes, VB Rocha, VC Carregari… - Frontiers in …, 2017 - frontiersin.org
… to secreted extracellular vesicles (… homeostasis and pathophysiological conditions. This
review presents the state-of-the-art proteomic technologies to identify and quantify EVs proteins

Proteomic analysis of protein homeostasis and aggregation

E Laskowska, D Kuczyńska-Wiśnik, B Lipińska - Journal of proteomics, 2019 - Elsevier
protein homeostasis, cells have evolved a network of evolutionarily conserved protective
mechanisms called protein … involve delivery of a substrate by the vesicles. In CMA, cytoplasmic …

Serotonin transporter associated protein complexes are enriched in synaptic vesicle proteins and proteins involved in energy metabolism and ion homeostasis

J Haase, J Grudzinska-Goebel, HK Muller… - ACS chemical …, 2017 - ACS Publications
… Here we describe the identification of SERT interacting proteins using three independent
proteomic screens as well as gene ontology analysis to gain advanced insight into the …

Hidden proteome of synaptic vesicles in the mammalian brain

Z Taoufiq, M Ninov, A Villar-Briones… - Proceedings of the …, 2020 - National Acad Sciences
… Moreover, proteins in the SV fraction are associated with … proteins was found in the low-abundance
proteome range, highlighting its pathological significance. Our deep SV proteome will …

Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts

Z Xiao, CE Camalier, K Nagashima… - Journal of cellular …, 2007 - Wiley Online Library
… to bone formation and homeostasis require the involvement of … osteoblasts generate and
secrete matrix vesicles (MVs) into the … function and biogenesis, a proteomic analysis of MVs has …

Proteomic insights into extracellular vesicle biology–defining exosomes and shed microvesicles

DW Greening, R Xu, SK Gopal, A Rai… - … review of proteomics, 2017 - Taylor & Francis
… of sample preparation and EV purification to verify the effectiveness of the selected strategy
via the robust characterization of the obtained vesicles prior to proteomic applications. …

Post-translational and transcriptional dynamics–regulating extracellular vesicle biology

B Claridge, K Kastaniegaard, A Stensballe… - … Review of Proteomics, 2019 - Taylor & Francis
… Along with alternative splicing, they provide the proteome with an enormous capacity for …
modified proteins have been detected in extracellular vesicles (EVs) – nano-membrane vesicles

A conditional proteomics approach to identify proteins involved in zinc homeostasis

T Miki, M Awa, Y Nishikawa, S Kiyonaka… - Nature …, 2016 - nature.com
proteomics approach to unveiling zinc homeostasis in detail by identifying proteins that …
characterize these zinc-rich vesicles on the basis of our conditional proteomics data. It was …