Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin.

ME Abood, JB Hurley, MC Pappone, HR Bourne… - Journal of Biological …, 1982 - Elsevier
coupling protein binds to its detector proteincoupling protein from its detector and promotes
activation of the effector enzyme (3, 8, 18). A recent report (19) that the ROS coupling protein

Chemotaxis in Vibrio cholerae

MA Boin, MJ Austin, CC Häse - FEMS microbiology letters, 2004 - academic.oup.com
… roles of these proteins have not been fully elucidated, the CheD protein is involved in receptor
activation, whereas the CheV protein functions as an adaptation and coupling protein [10]. …

In vivo cross‐linking of EpsG to EpsL suggests a role for EpsL as an ATPase‐pseudopilin coupling protein in the Type II secretion system of Vibrio cholerae

MD Gray, M Bagdasarian, WGJ Hol… - Molecular …, 2011 - Wiley Online Library
… of proteins, including several virulence factors. This system is homologous to the type IV pilus
biogenesis machinery and contains five proteins… bitopic inner membrane protein EpsL and …

Vibrio cholerae Hcp, a secreted protein coregulated with HlyA

SG Williams, LT Varcoe, SR Attridge… - Infection and …, 1996 - Am Soc Microbiol
protein of Vibrio cholerae regulated coordinately with the hemolysin, HlyA. Both proteins show
cholerae in vivo. We have identified and sequenced two genes for Hcp, designated hcpA …

Mucosal immunization with a bacterial protein antigen genetically coupled to cholera toxin A2/B subunits.

G Hajishengallis, SK Hollingshead, T Koga… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
… of a streptococcal protein adhesin. This construct was expressed in Escherichia coli as a
chimeric protein that retained … The protein composition of chromatographically purified chimeric …

Cholera toxin: a paradigm of a multifunctional protein

K Bharati, NK Ganguly - Indian Journal of Medical Research, 2011 - journals.lww.com
Cholera toxin (CT) was discovered exactly half a century ago by SN De. We have come a
long way since this epoch-making discovery. Retrospectively, science had to wait a long time …

Proteomic analysis of Vibrio cholerae outer membrane vesicles

E Altindis, Y Fu, JJ Mekalanos - Proceedings of the …, 2014 - National Acad Sciences
… digestion coupled to mass spectrometry to identify 90 proteins present in OMVs of Vibrio
cholerae when grown under conditions that activate the TCP pilus virulence regulatory protein (…

Vibrio cholerae: cholera toxin

DV Broeck, C Horvath, MJS De Wolf - … journal of biochemistry & cell biology, 2007 - Elsevier
… The bacterial protein toxin of Vibrio cholerae, cholera toxin, is a major agent involved in
severe diarrhoeal disease. Cholera toxin is a member of the AB toxin family and is composed of …

Direct Interaction of the EpsL and EpsM Proteins of the General Secretion Apparatus in Vibrio cholerae

M Sandkvist, LP Hough, MM Bagdasarian… - Journal of …, 1999 - Am Soc Microbiol
… In addition, when the L and M proteins were coexpressed in … two proteins interact in vivo
and that no other Eps protein is … autophosphorylating cytoplasmic membrane protein EpsE, we …

Sodium and proton coupling in the conformational cycle of a MATE antiporter from Vibrio cholerae

DP Claxton, KL Jagessar, PR Steed… - Proceedings of the …, 2018 - National Acad Sciences
… The current mechanistic understanding of ion-coupled substrate transport has been … of
NorM from Vibrio cholerae (NorM-Vc), a MATE transporter proposed to be coupled to both Na + …