… protein secretion system in Vibrio cholerae using the Dictyostelium host model system. …
Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the …

… cholerae employs is the type VI secretion system (T6SS), a harpoon-like macromolecular
apparatus that delivers toxic proteins (referred to as effectors) into the external milieu and into …

… disease cholera remains unclear (3). Although the structure of the secretion apparatus has
… , structural similarities to the bacteriophage cell-puncturing device have been identified (7, 8)…

… apparatus within the cell envelope. However, only limited evidence for specific … In this study,
we extend the analysis of the secretion apparatus ofV. cholerae by characterizing two of its …

… cholerae encodes a protein secretion system distinct from type III and type IV pathways. …
system constitutes the prototype of a secretion system that we propose to call “type VI secretion” …

… that the type VI secretion system (T6SS), which serves as a predatory killing device, is part
of the competence regulon in the naturally transformable pathogen Vibrio cholerae. The T6SS-…

… cholerae bacteria found as environmental isolates. Typically, they lack the ctx and tcp
genes and do not cause cholera … a protein secretion system, the type VI secretion system (T6SS), …

… III secretion system (TTSS) that is related to the TTSS2 gene cluster found in a pandemic clone
of Vibrio parahaemolyticus. The genes for this V. cholerae TTSS system … cholerae may be …

… structural components of the apparatus (vcsRTCNS2, … secretion system (analyzed by SignalP;
data not shown); similarly, in V. parahaemolyticus, the TDH and TRH proteins are secreted …

… cholerae contains a type II secretion system in addition to its T6SS [33]. We deleted EpsD
(VC2733), the outer membrane channel of type II secretion system. The secreted proteins from …