… cholera toxin and T2SS pseudopilus tip, we provide a structural basis for a possible secretion
… on a large exoprotein, the ∼85-kDa cholera toxin, and our recent crystal structure of the tip …

… The type VI secretion system (T6SS) is a proteinaceous weapon used by many Gram‐negative
bacteria to deliver toxins into adjacent target cells. Vibrio cholerae, the bacterium …

… , we assessed both the secretion of toxin subunits and the expression of an epsE-lacZ
transcriptional fusion in wt and toxR mutant backgrounds. For the secretion experiment, we used a …

… Once attached, the bacterium secretes its toxin which is accompanied by the release of
hemagglutinin/protease (HA/protease). This extracellular HA/protease is responsible for nicking …

… A gene essential for the secretion of cholera toxin from the periplasm of Vibrio cholerae into
… gene products required for extracellular protein secretion in several other Gram- organisms. …

… coli are linearunnicked polypeptide chains (18, 19, 27), whereas the A subunit of cholera
toxin secreted by V. cholerae is-proteolytically nicked (4, 15). We isolated the LTs secreted from …

… mechanisms in cholera toxin-induced secretion in rabbit ileal mucosa in vitro. Clin. Sci. …
Role of prostaglandins and cAMP in the secretory ef fects of cholera toxin. Science 245:857-…

… Cholera toxin secretion is dependent upon the extracellular protein secretion apparatus …
Both classical and El Tor vcpD mutants displayed significant cholera toxin secretion defects …

… be secreted even in the absence of CTA, there appears to be a mechanism to normally ensure
exit of fully assembled toxin (and no wasteful secretion … by the presence of cholera toxin A-…

… Interestingly, in contrast to our results with cholera toxin, the secretion of nuclease from
Serratia marcescens was blocked at low pH, while CCCP had no effect in this system. This …