[HTML][HTML] The role of Kupffer cells in hepatitis B and hepatitis C virus infections

A Boltjes, D Movita, A Boonstra, AM Woltman - Journal of hepatology, 2014 - Elsevier
… /macrophages and other myeloid cells. In this review we discuss our current understanding
of Kupffer cells, and assess their role in the regulation of anti-viral immunity and disease …

Kupffer cells and their function

EN Wardle - Liver, 1987 - Wiley Online Library
… In inflammatory states with hepatocellular damage such as virus hepatitis, chronic active
hepatitis and primary biliary cirrhosis, there is enhanced Kupffer cell activity (39, 85, 125). It is …

Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis

G Sitia, M Iannacone, R Aiolfi, M Isogawa… - PLoS …, 2011 - journals.plos.org
viral hepatitis (where liver damage is triggered, as during viral hepatitis in humans, by
virus-specific CD8 T cells… affect the pathogenic potential of virus-specific CD8 T cells. Instead, KCs …

[HTML][HTML] Role of Kupffer cells in the pathogenesis of liver disease

G Kolios, V Valatas, E Kouroumalis - World journal of …, 2006 - ncbi.nlm.nih.gov
Kupffer cells may be implicated in the pathogenesis of various liver diseases including viral
hepatitis, … paper, suggesting that Kupffer cells may act both as effector cells in the destruction …

Type I interferon receptor signaling delays Kupffer cell replenishment during acute fulminant viral hepatitis

K Borst, T Frenz, J Spanier, PK Tegtmeyer… - Journal of …, 2018 - Elsevier
… in acute viral hepatitis. We identified that during infection with DNA-encoded viruses, type
1 … of monocyte-derived Kupffer cells. This points to new therapeutic strategies for acute …

Kupffer cells in immune activation and tolerance toward HBV/HCV infection.

F Yuan, W Zhang, D Mu, J Gong - Advances in Clinical & …, 2017 - search.ebscohost.com
… Studies on the role of KCs in viral hepatitis are beneficial to the body of knowledge on this
disease, and can help us not only to get a better understanding of the pathogenesis of HBV/…

The Kupffer cell reaction in murine and human viral hepatitis, with particular reference to the origin of acidophilic bodies

B Ruebner, K Miyai - The American Journal of Pathology, 1962 - ncbi.nlm.nih.gov
… parenchymal and a sinusoidal lining cell. The principal object … in viral hepatitis occurred in
endothelial or parenchymal cells. … cell type,3 we have treated the terms sinusoidal lining cell, …

Involvement of TRAIL and its receptors in viral hepatitis

B Mundt, F Kühnel, L Zender, Y Paul… - The FASEB …, 2003 - Wiley Online Library
… infection is not dependent on lymphocytes, NK, or Kupffer cells, we hypothesized that the
TRAIL receptor/ligand system is a paracrine mechanism of hepatocytes against virally infected …

Expression of co-stimulatory molecules by Kupffer cells in chronic hepatitis of hepatitis C virus etiology

VL Burgio, G Ballardini, M Artini, M Caratozzolo… - Hepatology, 1998 - journals.lww.com
… In this paper we show that in viral hepatitis most Kupffer cells (… the phenotype of professional
antigen presenting cells (APCs). … The positivity of activated KCs for hepatitis C virus (HCV) …

Hepatic immune regulation and its involvement in viral hepatitis infection

PA Knolle, R Thimme - Gastroenterology, 2014 - Elsevier
… network, where hepatocytes are separated from blood passing through the sinusoids by
stellate cells, LSECs, and Kupffer cells. Interestingly, LSECs and lymphatic endothelial …