Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function

J Melchjorsen, LN Sørensen… - Journal of Leucocyte …, 2003 - academic.oup.com
… Another prominent response to viral infection is the expansion and activation of CD4+
and CD8+ T cells, which have central roles in antiviral immunity and work through various …

Activation and function of natural killer cell responses during viral infections

CA Biron - Current opinion in immunology, 1997 - Elsevier
… Once T cell responses are activated, additional mechanisms are in place to turn off NK
cell functions. These studies demonstrate that viral infections elicit unique mechanisms for …

Interferons and viral infections

V Fensterl, GC Sen - Biofactors, 2009 - Wiley Online Library
… and macrophage activation and the … of activated Th1 cells during the adaptive immune
response. Furthermore, IFN-γ regulates NK and B cell functions as well as macrophage activation, …

Natural killer cell responses to viral infection

JD Brandstadter, Y Yang - Journal of innate immunity, 2011 - karger.com
… cell activation and function in the control of viral infections will … activated in response to viral
infections. We will then focus on the recruitment of activated NK cells to the site of infection as …

[HTML][HTML] Inflammasomes and its importance in viral infections

G Shrivastava, M León-Juárez, J García-Cordero… - Immunologic …, 2016 - Springer
… A growing body of evidence regarding the mechanisms of inflammasome activation suggests
that in several viral infections, viral products such as viroporins may alter cell membrane …

[HTML][HTML] Direct TLR2 signaling is critical for NK cell activation and function in response to vaccinia viral infection

J Martinez, X Huang, Y Yang - PLoS pathogens, 2010 - journals.plos.org
… NK cell activation and function. Collectively, … cell activation and function in the control of a
viral infection in vivo, indicate that multiple pathways are required for efficient NK cell activation, …

Induction and function of type I and III interferon in response to viral infection

DE Levy, IJ Marié, JE Durbin - Current opinion in virology, 2011 - Elsevier
activation of the IFNβ promoter in response to viral infection [13]. Requirement for a higher
order assembly of multiple transcription factor components for effective transcription of the IFN-…

[HTML][HTML] Viral infections activate types I and III interferon genes through a common mechanism

K Onoguchi, M Yoneyama, A Takemura, S Akira… - Journal of Biological …, 2007 - ASBMB
… genes are regulated by viral infections. We took … of function of the signaling molecules critical
for type I IFN genes. We mapped and analyzed cis-regulatory elements that function as virus

Sensing of viral infection and activation of innate immunity by toll-like receptor 3

E Vercammen, J Staal, R Beyaert - Clinical microbiology reviews, 2008 - Am Soc Microbiol
… a role for TLR3 in hepatitis C virus infection, the physiological function of TLR3 in hepatitis
… C virus-TLR3 interaction has come from biopsy specimens of patients with hepatitis C virus-…

Central roles of NLRs and inflammasomes in viral infection

TD Kanneganti - Nature Reviews Immunology, 2010 - nature.com
viral infections. NLR proteins were previously thought to be the only mediators of inflammasome
activation. … The requirement for NLRP3 inflammasome activation during virus infection in …