… role of the HBZ protein in HTLV-1 pathogenesis, little is known as to how this viral gene is …
, we show that the viral Tax protein upregulates antisense transcription through its action on …

… antisense transcripts are also involved in the production of retroviral proteins that we have
termed Antisense Protein of … virus type 1 antisense transcription by the viral tax protein. J. Virol. …

… antisense transcripts is not always demonstrably associated with the presence of an antisense
open reading frame encoding a viral protein. … -1 can direct antisense transcription in a Tax-…

… of Tax and HBZ. We found that sense transcription did not interfere with antisense transcription
… Consistent with these observations, Tax did not regulate antisense transcription in our …

… of the antisense viral protein HBZ in down-regulating the NF-κB activation induced by Tax,
and … as compared to that exerted by the HTLV-2 antisense protein, APH-2. Finally, we discuss …

… important activating potential of the viral Tax protein on HTLV-1 5… results demonstrating that
antisense transcripts also exist in … role of antisense transcription and resulting viral proteins in …

… of antisense transcripts in these new viruses and their potential coding capacity. Our results
indicate that both viruses produce a spliced and polyadenylated antisense transcript. The …

… region that encodes a viral Tax transactivator protein, and several accessory proteins. Whereas
HTLV-… primary role played by the viral protein in the maintenance of a transformed stage. …

… Tax-mediated activation of key cellular pathways, including CREB, the canonical NF-κB
pathway, and AP1 pathways, all of which are involved in viral … Downregulation of Tax-mediated …

… of Tax mediated viral transcription postulated as a vital part of the … BLV antisense transcription
appears to be a consistent feature of BLV infections. We also find that one of the transcripts …