Replication and assembly of human papillomaviruses

MJ Conway, C Meyers - Journal of dental research, 2009 - journals.sagepub.com
… , native HPV virions are only produced in vivo or in organotypic “raft” culture. Research
producing synthetic papillomavirus particles—such as virus-like particles (VLPs), papillomavirus-…

[HTML][HTML] Human Papillomavirus (HPV) virion induced cancer and subfertility, two sides of the same coin

CE Depuydt, J Beert, E Bosmans… - Facts, views & vision in …, 2016 - ncbi.nlm.nih.gov
… both virus and virions since they contain the same viral DNA. Because viral HPV DNA can
be present in both virions and virus and in both non- dividing virion producing cells as well as …

Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity

CM Hebner, LA Laimins - Reviews in medical virology, 2006 - Wiley Online Library
… HPV virions infect the dividing cells of the basal layer. Unlike normal epithelium where cells
… -infected cells maintain cell division to allow for genome amplification and virion production

Production of infectious human papillomavirus independently of viral replication and epithelial cell differentiation

D Pyeon, PF Lambert… - Proceedings of the …, 2005 - National Acad Sciences
papillomavirus replication and virion production are tied to epithelial cell differentiation,
infectious papillomavirus virion production … or mutant human papillomavirus (HPV) virions have …

Production of human papillomavirus type 16 virions in a keratinocyte cell line

J Sterling, M Stanley, G Gatward, T Minson - Journal of virology, 1990 - Am Soc Microbiol
production in vivo of infectious human papillomavirus type 11… infection with human papilloma
virus type 1 of human hand … Human papillomavirus type 16 DNA cooperates with activated …

Production of human papillomavirus and modulation of the infectious program in epithelial raft cultures. OFF.

SC Dollard, JL Wilson, LM Demeter… - Genes & …, 1992 - genesdev.cshlp.org
… By using a variation of the keratinocyte raft culture technique, we have achieved the first
production of papillomavirus virions in vitro. In contrast, only low levels of E-region mRNAs …

Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation

C Meyers, MG Frattini, JB Hudson, LA Laimins - Science, 1992 - science.org
papillomaviruses found in clinical samples. Human papillomaviruses (HPVs) are important
human … of keratinocytes in which virion production is limited to differentiating suprabasal cells (…

In vitro generation and type-specific neutralization of a human papillomavirus type 16 virion pseudotype

RB Roden, HL Greenstone, R Kirnbauer… - Journal of …, 1996 - Am Soc Microbiol
… correct HPV31b virions have been produced by this method, but … produced infectious
papillomavirus by expressing the virionProduction of infectious BPV was monitored by a …

In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression.

MG Frattini, HB Lim, LA Laimins - Proceedings of the …, 1996 - National Acad Sciences
… that virion production could be achieved from continuous cell lines that maintained HPV
genomes as episomes. It therefore seemed possible that virion … We conclude that HPV 31 virions

Pathogenesis of human papillomaviruses in differentiating epithelia

MS Longworth, LA Laimins - Microbiology and molecular biology …, 2004 - Am Soc Microbiol
… in the generation of progeny virions. Since virion production is restricted to differentiated
cells, … The L1 and L2 proteins form icosahedral capsids for progeny virion generation. The …