Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
… in the extraordinarily high number of toxins and other virulence determinants that S. aureus
produces and how they impact disease. In this review, we will give an overview of how S. …

The role of antibiotics in modulating virulence in Staphylococcus aureus

E Hodille, W Rose, BA Diep, S Goutelle… - Clinical microbiology …, 2017 - Am Soc Microbiol
Staphylococcus aureus is often involved in severe infections, in which the effects of bacterial
virulence … of antibacterial agents on the expression of virulence factors and on the host's …

The evolution and maintenance of virulence in Staphylococcus aureus: a role for host-to-host transmission?

RC Massey, MJ Horsburgh, G Lina, M Höök… - Nature Reviews …, 2006 - nature.com
… establishment and maintenance of microbial virulence remain enigmatic. To … Staphylococcus
genus — Staphylococcus aureus and Staphylococcus epidermidis — and consider why S

Regulation of Staphylococcus aureus Virulence

C Jenul, AR Horswill - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a complex
regulatory network to control virulence. … the production of virulence factors necessary for …

Regulation of virulence in Staphylococcus aureus: molecular mechanisms and remaining puzzles

B Wang, TW Muir - Cell chemical biology, 2016 - cell.com
The agr locus encodes a quorum-sensing (QS) circuit required for the virulence of a spectrum
of Gram-positive pathogens and is, therefore, regarded as an important target for the …

Molecular Basis of Virulence in Staphylococcus aureus Mastitis

…, P François, J Schrenzel, M Van De Guchte, S Even… - PLoS …, 2011 - journals.plos.org
… In particular, O11 produced relatively high levels of exoproteins, including toxins and
proteases known to be important in virulence. A characteristic we observed in other S. aureus

Metabolic sensor governing bacterial virulence in Staphylococcus aureus

Y Ding, X Liu, F Chen, H Di, B Xu… - Proceedings of the …, 2014 - National Acad Sciences
… its virulence-associated properties. We define a key circuit of the virulence regulatory network
of S. aureus and emphasize that metabolic status may be a critical element governing the …

Large-Scale Identification of Genes Required for Full Virulence of Staphylococcus aureus

BM Benton, JP Zhang, S Bond, C Pope… - Journal of …, 2004 - Am Soc Microbiol
… SMIT tags were then mobilized into the virulent S. aureus SAM23 strain by transduction.
To confirm integration into the geh locus, culture supernatants derived from individual …

Population genetics and the evolution of virulence in Staphylococcus aureus

KYL Chua, BP Howden, JH Jiang, T Stinear… - Infection, Genetics and …, 2014 - Elsevier
… The population genetics of S. aureus and the evolution of virulence is the focus of this
review. We describe the various techniques in determining S. …

Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infection

WJ Weiss, E Lenoy, T Murphy, LA Tardio… - Journal of …, 2004 - academic.oup.com
Objective: The role that the surface proteins anchored by the srtA and srtB gene products
play in the ability of Staphylococcus aureus bacteria to establish infection was investigated in …