… immunodeficiency virus type 1 (HIV-… ceramide synthesis with the serine palymotyl transferase
inhibitor ISP-1 (10μM) significantly reduced gp120 and Tat-induced increases of ceramide …

… Sphingosine kinase 1 serves as a pro-viral factor by regulating viral RNA synthesis and
nuclear export of viral ribonucleoprotein complex upon influenza virus infection. PLoS One 2013;…

… Ceramide synthetic pathways and Cer synthases. (A) Synthetic pathways of Cers, the catalytic
enzymes of each reaction, and their related hereditary disorders. (B) Substrate specificity (…

… Outline of the Synthetic Plan. Here we report the first enantioselective total synthesis of a
regioisomer of 1, d-erythro-(5E)-ceramide (3), starting from commercially available and …

… This report described the synthesis of the 4-(4-fluorophenoxy)phenyl … The viruses used in
this study are influenza virus strain WSN (A/WSN/1933/H1N1) and Japanese encephalitis virus …

… ceramide analog, HT29 cells were able to synthesize several labeled sphingolipids, including
GalC (17). Whether these cells could synthesize … a basolateral incubation of the virus (10). …

… To determine that indeed sphingosine is responsible for interaction between HSV-1 and
ILVs, we generated liposomes and loaded them either with ceramide or sphingosine. …

… Although not all 293T cells were transduced with the XBP-1s-encoding viruses, we … Based
on the mass spectrometry data for ceramides and SM levels, the de novo ceramide synthesis …

… a virus-encoded protein phosphatase adaptor that promotes dephosphorylation of multiple
cellular and virus proteins, including the cellular ceramide (… infecting with a virus encoding the …

… To further develop sphingolipid metabolism-targeted therapies, we have designed and
synthesized a series of new ceramide analogs by introducing sulfonamide, amide, and/or certain …