Mechanisms underlying visceral hypersensitivity in irritable bowel syndrome

G Barbara, C Cremon, R De Giorgio, G Dothel… - Current …, 2011 - Springer
Visceral hypersensitivity is currently considered a key pathophysiological mechanism …
disorders, including irritable bowel syndrome (IBS). In IBS, visceral hypersensitivity has been …

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Methods to assess visceral hypersensitivity in irritable bowel syndrome

D Keszthelyi, FJ Troost… - American Journal of …, 2012 - journals.physiology.org
… of visceral pain/visceral nociception/visceral hypersensitivity” and “irritable bowel syndrome.”
… This review aims to discuss currently used modalities in assessing visceral perception, …

Role of visceral sensitivity in the pathophysiology of irritable bowel syndrome

M Delvaux - Gut, 2002 - gut.bmj.com
Visceral hypersensitivity has been recognised as a characteristic of patients with irritable
bowel syndrome (IBS). It may be involved in the pathogenesis of abdominal pain/discomfort, …

Visceral hypersensitivity in irritable bowel syndrome

M Kanazawa, M Hongo… - … of Gastroenterology and …, 2011 - Wiley Online Library
… In conclusion, visceral hypersensitivity is common in IBS patients and probably plays a major
… of the symptoms and both central and peripheral factors may enhance the pain sensitivity. …

[HTML][HTML] The role of visceral hypersensitivity in irritable bowel syndrome: pharmacological targets and novel treatments

MH Farzaei, R Bahramsoltani, M Abdollahi… - Journal of …, 2016 - ncbi.nlm.nih.gov
… by altered bowel habits, abdominal pain, and bloating. Visceral hypersensitivity (VH) is a …
therapies for modulation of persistent visceral hyperalgesia. The current paper reviews the …

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome

B Feng, JH La, ES Schwartz… - American Journal of …, 2012 - journals.physiology.org
Irritable bowel syndrome (IBS) is characterized as functional because a pathobiological
cause is not readily apparent. Considerable evidence, however, documents that sensitizing …

Visceral hypersensitivity in irritable bowel syndrome: molecular mechanisms and therapeutic agents

A Akbar, JRF Walters, S Ghosh - Alimentary pharmacology & …, 2009 - Wiley Online Library
hypersensitivity 8 defined by reduced pain and discomfort thresholds, 9, 10 which may …
associated with bowel disturbances. Although the pathogenesis of visceral hypersensitivity is not …

Markers for visceral hypersensitivity in patients with irritable bowel syndrome

S Ludidi, Z Mujagic, D Jonkers… - …, 2014 - Wiley Online Library
Irritable bowel syndrome (IBS) is a heterogenous disorder with visceral hypersensitivity
as … It is not known whether IBS patients with visceral hypersensitivity have different …

Evolution of visceral sensitivity in patients with irritable bowel syndrome

P Poitras, MR Poitras, V Plourde, M Boivin… - Digestive diseases and …, 2002 - Springer
… Here we examined the evolution of rectal sensitivity and of … Evolution of the gastrointestinal
index and rectal sensitivity … In conclusion, visceral hypersensitivity appeared as a stable …

[HTML][HTML] Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases

H Ceuleers, H Van Spaendonk, N Hanning… - World journal of …, 2016 - ncbi.nlm.nih.gov
… specifically on visceral sensitivity while … visceral hypersensitivity, further research is
warranted. The aim of this review is to give an overview on the concept of visceral hypersensitivity