… therapy response in prostate cancer 51 , and this role and mutational status should be kept
in mind when choosing appropriate prostate cancer cell lines for in vitro and in vivo studies (…

… models discussed in this review. There has been a wide variety of transgenic models developed
in which to study prostate cancer. … these models. Furthermore, at a recent meeting of the …

… model, as searches on PubMed for the term “prostate cancer … Preclinical in vivo studies are
difficult to translate to the … of different subpopulations of both cancer and stromal cells within a …

… recapitulated in these models. We describe the history of prostate cancer nomenclature, from
… We also discuss the development of different prostate cancer cell models in vitro, referring …

… prostate cancer model systems in use and defined their utility and limitations. This review will
guide the investigator seeking models … prostate cancer models either grow only in vivo as …

… Parallel in vitro and in vivo studies … six prostate cancer cell lines (ten datasets total) have
been extracted from the literature and re-analysed using the linearquadratic (LQ) survival model…

… Mouse prostate cancer modeling presents unique obstacles to the study of spontaneous …
of the prostate from normal and genetically engineered animals, in vivo. Additionally, MRS …

… events in vivo. We used this technology to develop a metastasis assay of human prostate
cancer (PCa) … or in the prostate (orthotopically) of severe combined immunodeficient mice as …

… In vivo prostate cancer models of human origin typically consist of primary cell or tissue
slice grafts [11], multiple cancer cell lines as grafts [12], [13], [14], [15], as well as …

… The only clinically approved prostate cancer–specific imaging agent, ProstaScint, involves
a … a model for PSMA-positive tumors and PC-3 (prostate cancer) and MCF-7 (breast cancer) …