Kappa opioid receptor-induced aversion requires p38 MAPK activation in VTA dopamine neurons
JM Ehrich, DI Messinger, CR Knakal… - Journal of …, 2015 - Soc Neuroscience
… that KOR activation of p38α MAPK in ventral tegmental (VTA) dopaminergic neurons was
required … of floxed KOR or floxed p38α MAPK by Cre recombinase expression in dopaminergic …
required … of floxed KOR or floxed p38α MAPK by Cre recombinase expression in dopaminergic …
Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1 …
S Karunakaran, U Saeed, M Mishra… - Journal of …, 2008 - Soc Neuroscience
… of p38 MAP kinase within the dopaminergic neurons, whereas JNK activation occurs … of
control animals while not detectable in ventral tegmental area (VTA) neurons. After single dose …
control animals while not detectable in ventral tegmental area (VTA) neurons. After single dose …
Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo
SH Choi, EH Joe, SU Kim, BK Jin - Journal of Neuroscience, 2003 - Soc Neuroscience
… p38 MAPK, and this microglial activation can mediate degeneration of dopaminergic neurons
… the TH-ip cells in the ventral tegmental area (VTA), or both. The ventral border followed the …
… the TH-ip cells in the ventral tegmental area (VTA), or both. The ventral border followed the …
The role of ERK1, 2, and 5 in dopamine neuron survival during aging
MS Parmar, JD Jaumotte, SL Wyrostek, MJ Zigmond… - Neurobiology of …, 2014 - Elsevier
… VTA dopaminergic neurons. This is the first study to examine ERK1, 2, and 5 expression and
activation in the SN, STR, and VTA … of SN and VTA dopaminergic neurons. These data raise …
activation in the SN, STR, and VTA … of SN and VTA dopaminergic neurons. These data raise …
[HTML][HTML] Functions of p38 MAP kinases in the central nervous system
… The p38 MAP kinase signaling pathway. (A) Dendrogram of … Similarly, p38α acts in
dopaminergic neurons to regulate … Activated p38α in presynaptic VTA neurons phosphorylate …
dopaminergic neurons to regulate … Activated p38α in presynaptic VTA neurons phosphorylate …
Regulations of methamphetamine reward by extracellular signal-regulated kinase 1/2/ets-like gene-1 signaling pathway via the activation of dopamine receptors
H Mizoguchi, K Yamada, M Mizuno, T Mizuno… - Molecular …, 2004 - ASPET
… activated by stress stimuli. In this study, no changes in phosphorylated levels of JNK and p38
MAPK … or chronic infusion of BDNF induces ERK activation in the VTA, and the morphine-…
MAPK … or chronic infusion of BDNF induces ERK activation in the VTA, and the morphine-…
ErbB4 regulate extracellular dopamine through the p38 MAPK signaling pathway
S Cao, C Wen, R Sun, J Han, Y Sun, X Xu, X Li… - Neuroscience …, 2021 - Elsevier
… Dopamine is the major product of SN and VTA dopaminergic neurons, while the LC neurons
… For instance, the loss of dopaminergic neurons in the SN is the primary cause for motor …
… For instance, the loss of dopaminergic neurons in the SN is the primary cause for motor …
Dopamine: functions, signaling, and association with neurological diseases
… receptor activation in normal brain function. Furthermore, we describe the potential …
Following synthesis in dopaminergic neurons, dopamine is sequestered into the acidic lumen of …
Following synthesis in dopaminergic neurons, dopamine is sequestered into the acidic lumen of …
Activation of p38 MAPK in the substantia nigra leads to nuclear translocation of NF‐κB in MPTP‐treated mice: implication in Parkinson's disease
S Karunakaran, V Ravindranath - Journal of neurochemistry, 2009 - Wiley Online Library
… not activated in the neurons of the ventral tegmental area (VTA) … dysfunction in dopaminergic
neurons by inhibiting complex I of … MPP + also activates the MAPK by phosphorylating p38. …
neurons by inhibiting complex I of … MPP + also activates the MAPK by phosphorylating p38. …
[HTML][HTML] Is p38 MAPK associated to drugs of abuse-induced abnormal behaviors?
R El Rawas, IM Amaral, A Hofer - International Journal of Molecular …, 2020 - mdpi.com
… Importantly, cell-specific deletion of p38α MAPK in serotonergic neurons blocked stress-…
neurons of the DRN or in the dopaminergic neurons of the VTA of KOR KO mice activated p38 …
neurons of the DRN or in the dopaminergic neurons of the VTA of KOR KO mice activated p38 …
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