Waning protection after fifth dose of acellular pertussis vaccine in children

NP Klein, J Bartlett, A Rowhani-Rahbar… - … England Journal of …, 2012 - Mass Medical Soc
… Nonetheless, in 2010, California had a large pertussis outbreak, 10 with the highest … quantify
the waning of DTaP protection against pertussis over time in a highly vaccinated population …

What is wrong with pertussis vaccine immunity? The problem of waning effectiveness of pertussis vaccines

N Burdin, LK Handy, SA Plotkin - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
… After both a three-dose and five-dose primary series of aP, protection predictably wanes
after the last dose of the series, with the odds of pertussis increasing by 1.33 times (95% CI 1.23…

Waning vaccine immunity in teenagers primed with whole cell and acellular pertussis vaccine: recent epidemiology

SL Sheridan, K Frith, TL Snelling… - Expert review of …, 2014 - Taylor & Francis
waning of protection following boosting and inadequate control of pertussis of the existing
schedule in this well-vaccinated … Point vaccine effectiveness was substantially higher among …

Waning immunity to pertussis following 5 doses of DTaP

SY Tartof, M Lewis, C Kenyon, K White, A Osborn… - …, 2013 - publications.aap.org
pertussis vaccine (DTaP), rates of pertussis have increased substantially in 7- to 10-year-olds
in recent years. Duration of protection … role of vaccine formulation on duration of protection. …

Effectiveness of pertussis vaccination and duration of immunity

KL Schwartz, JC Kwong, SL Deeks, MA Campitelli… - Cmaj, 2016 - Can Med Assoc
… of the pertussis vaccine and characterize the effect of waning immunity and whole-cell … 7
years since the last vaccination there is minimal protective effect of the vaccine, despite some …

[HTML][HTML] Waning protection following 5 doses of a 3-component diphtheria, tetanus, and acellular pertussis vaccine

NP Klein, J Bartlett, B Fireman, L Aukes, PO Buck… - Vaccine, 2017 - Elsevier
… In conclusion, there is substantial waning of protection against pertussis as children … Risk
of contracting pertussis increased on average by 27% per year since vaccination after the 5 th …

Duration of protection after first dose of acellular pertussis vaccine in infants

HE Quinn, TL Snelling, KK Macartney… - Pediatrics, 2014 - publications.aap.org
Waning of pertussis antibodies to 4 years among infants who did and did not receive
monovalent acellular pertussis vaccine at birth. In: 13th National Immunisation Conference; June 19…

Estimating the effectiveness of tetanus-diphtheria-acellular pertussis vaccine (Tdap) for preventing pertussis: evidence of rapidly waning immunity and difference in …

R Koepke, JC Eickhoff, RA Ayele… - The Journal of …, 2014 - academic.oup.com
… In conclusion, our results provide evidence of waning protection from Tdap vaccination
among both Adacel and Boostrix recipients. Boostrix was more effective than Adacel in …

A call for caution in use of pertussis vaccine effectiveness studies to estimate waning immunity: a Canadian Immunization Research Network Study

NS Crowcroft, KL Schwartz, RD Savage… - Clinical Infectious …, 2021 - academic.oup.com
… cases that meet a typical case definition falls with age after infancy, which means that both
designs may have underestimated waning of protection against milder and atypical infection. …

A change in vaccine efficacy and duration of protection explains recent rises in pertussis incidence in the United States

M Gambhir, TA Clark, S Cauchemez… - PLoS computational …, 2015 - journals.plos.org
… Since our calculated waning rate is an average over the whole population, this means
some individuals will re-enter the susceptible pool more quickly than others. By simulating a …