The EMPOWER study: randomized, prospective, double-blind, multicenter trial of vagal blockade to induce weight loss in morbid obesity

MG Sarr, CJ Billington, R Brancatisano, A Brancatisano… - Obesity surgery, 2012 - Springer
… to mean duration of vagal blockade per day, the weight loss was greater … Those subjects
who wore the vagal blockade device … beneficial effect of vagal blockade on weight loss. Lack of …

Effect of reversible intermittent intra-abdominal vagal nerve blockade on morbid obesity: the ReCharge randomized clinical trial

S Ikramuddin, RP Blackstone, A Brancatisano, J Toouli… - Jama, 2014 - jamanetwork.com
… In this study of patients with morbid obesity, the percentage of excess weight loss among
participants treated with vagal block did not meet either of the coprimary efficacy objectives, …

Sustained weight loss with vagal nerve blockade but not with sham: 18‐month results of the recharge trial

SA Shikora, BM Wolfe, CM Apovian, M Anvari… - Journal of …, 2015 - Wiley Online Library
Vagal nerve blockade (vBloc) has been recently studied as a minimally invasive laparoscopic
surgery for weight loss and improvement in weight-… procedures for weight loss, Roux-en-Y …

[HTML][HTML] Two-year outcomes of vagal nerve blocking (vBloc) for the treatment of obesity in the ReCharge trial

CM Apovian, SN Shah, BM Wolfe, S Ikramuddin… - Obesity surgery, 2017 - Springer
vagal blockade using the vBloc device for 24 months in the ReCharge Trial demonstrated
sustained weight loss, … Vagal block treated participants achieved 21 % EWL (8 % TWL) at 24 …

Vagal blocking for obesity control: a possible mechanism-of-action

H Johannessen, D Revesz, Y Kodama, N Cassie… - Obesity surgery, 2017 - Springer
… letter, ie, “the specific mechanisms for weight loss due to the use of the device are unknown”…
1, and PYY), indicating a functional blockade of vagal efferent fibers, named as VBLOC. The …

American Society for Metabolic and Bariatric Surgery position statement on vagal blocking therapy for obesity

P Papasavas, M El Chaar, SN Kothari - Surgery for Obesity and Related …, 2016 - soard.org
… (FDA) of a new device for weight loss called vagal blocking therapy for obesity (VBLOC) in
… Sustained weight loss with vagal nerve blockade but not with sham: 18-month results of the …

[HTML][HTML] Effect of vagal nerve blockade on moderate obesity with an obesity-related comorbid condition: the ReCharge study

JM Morton, SN Shah, BM Wolfe, CM Apovian, CJ Miller… - Obesity surgery, 2016 - Springer
… studied, the 1-year weight loss reported provides support that vagal blockade may be
considered an effective alternative to conventional weight loss surgery particularly in this moderate …

Intermittent vagal nerve block for improvements in obesity, cardiovascular risk factors, and glycemic control in patients with type 2 diabetes mellitus: 2-year results of …

SA Shikora, J Toouli, MF Herrera, B Kulseng… - Obesity surgery, 2016 - Springer
vagal nerve block among obese patients with T2DM. Efficacy measures of interest were
improvements from baseline in percentage excess weight loss (%EWL), percent total weight loss

Role of the vagus nerve in the development and treatment of diet‐induced obesity

G de Lartigue - The Journal of physiology, 2016 - Wiley Online Library
Vagal blockade is proposed to inhibit aberrant … of vagal blockade-induced weight loss.
Approaches and molecular targets to develop future pharmacotherapy targeted to the vagus

Intra-abdominal vagal blocking (VBLOC therapy): clinical results with a new implantable medical device

M Camilleri, J Toouli, MF Herrera, B Kulseng, L Kow… - Surgery, 2008 - Elsevier
vagal blocking causes weight loss and that this is associated with evidence of vagal … a
defined electrical algorithm and maintained vagal block, additional studies are underway …