Impact of weight on the efficacy and safety of direct-acting oral anticoagulants in patients with non-valvular atrial fibrillation: a meta-analysis

AH Malik, S Yandrapalli, S Shetty, WS Aronow… - EP …, 2020 - academic.oup.com
… This study sought to determine the impact of weight and body mass index (BMI) on the
safety and efficacy of direct-acting oral anticoagulants (DOACs) compared with warfarin in …

[HTML][HTML] Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and …

K Boonyawat, F Caron, A Li… - Journal of Thrombosis …, 2017 - Elsevier
oral anticoagulant (DOAC)‐treated patients about safety and efficacy in extremes of body
weight… The aims of this systematic review were to investigate the association of body weight

Effect of body weight on efficacy and safety of direct oral anticoagulants in the treatment of patients with acute venous thromboembolism: a meta-analysis of …

MND Di Minno, R Lupoli, A Di Minno… - Annals of …, 2015 - Taylor & Francis
… (VTE), anticoagulation is mandatory to prevent thrombus … -weight heparin (LMWH) followed
by oral anticoagulation with … efficacy of DOACs compared to VKA in obese, normal-weight

Evaluation of safety and efficacy outcomes of direct oral anticoagulants versus warfarin in normal and extreme body weights for the treatment of atrial fibrillation or …

AR Novak, C Shakowski, TC Trujillo, GC Wright… - Journal of Thrombosis …, 2022 - Springer
… use of direct oral anticoagulants (DOACs) in patients with extremes of body weight remains
… to warfarin on safety and efficacy outcomes in extreme body weight patients. This multi-center…

Effectiveness and safety of direct oral anticoagulants in patients with nonvalvular atrial fibrillation and weighing≥ 120 kilograms versus 60–120 kilograms

EE Wiethorn, CM Bell, BS Wiggins - American Journal of Cardiovascular …, 2021 - Springer
… One might assume that the majority of the primary outcome events occurred in those at the
higher extreme of body weight, however this was not found to be the case in the present study…

Efficacy and safety of direct oral anticoagulants for atrial fibrillation across body mass index categories

RM Kaplan, Y Tanaka, RS Passman… - Journal of the …, 2020 - Am Heart Assoc
anticoagulation in patients with AF and elevated body weight has become even more
essential to address in routine clinical practice. The purpose of this study was to evaluate efficacy

Direct oral anticoagulants in patients with nonvalvular atrial fibrillation and low body weight

SR Lee, EK Choi, CS Park, KD Han, JH Jung… - Journal of the American …, 2019 - jacc.org
… From a total of 135,939 new users of oral anticoagulants (OACs) since January 2014, 7,576
warfarin users and 14,103 direct oral anticoagulant (DOAC) users were included in this study…

Anticoagulation at the extremes of body weight: choices and dosing

GJB McCaughan, EJ Favaloro, L Pasalic… - Expert review of …, 2018 - Taylor & Francis
… higher doses to be required with increasing body weight. Monitoring of INR to achieve a
therapeutic range ensures effective and safe oral anticoagulation even in those with Class II and …

Safety and efficacy of direct oral anticoagulants across body mass index groups in patients with venous thromboembolism: a retrospective cohort design

RM Cardinal, F D'Amico, A D'Addezio, K Dakers… - Journal of Thrombosis …, 2021 - Springer
… the safety and efficacy of direct oral anticoagulants (DOACs) in patients of extreme weights
are … the safety and efficacy of DOAC therapy in patients of extreme weights for the treatment of …

The non-vitamin K antagonist oral anticoagulants (NOACs) and extremes of body weight—a systematic literature review

R De Caterina, GYH Lip - Clinical Research in Cardiology, 2017 - Springer
… antagonist oral anticoagulants (NOACs) exert their anticoagulantweight (and its correlates,
ie, surface area and body mass index, BMI), extremes in body weight may affect their efficacy