… Werner syndrome (WS) is an autosomal recessive progeroid disorder caused by mutations
… in their 30s or 40s, but the early pathophysiology of the syndrome is still not fully understood. …

… , the loss of sex maturation and voice change or the early onset of cataract. Reliable records,
particularly of early pathophysiological manifestations of WS, are therefore limited. As listed …

… Recent cases of increasingly elderly Werner Syndrome (WS) patients have paralleled
increased lifespan in … Reliable records, particularly of early pathophysiological manifestations of …

… Werner syndrome (WS) is an autosomal recessive disease manifested by the premature …
it a focus of recent molecular studies on the pathophysiology of aging. In culture, cells obtained …

… gene causes Werner Syndrome (WS). WS patients with genetic instability manifest an early
onset of … , atherosclerosis, and malignancy as well as early death. In 1,420 patients, WS was …

… advance our understanding of the pathophysiology of WS. … Werner Syndrome (WS) is an
autosomal recessive genetic … in a single gene, the Werner syndrome gene (WRN), which …

… the diagnosis of Werner syndrome in our newly assembled case population using
standard diagnostic criteria established by the International Registry of Werner Syndrome (http://www.…

… Werner syndrome and Hutchinson- Gilford progeria syndrome are the best characterized
human disorders. Werner syndrome patients have a median life expectancy of 47 years with …

… Collectively, the term: inflammaging has been proposed to explain pathophysiology of …
(MMP-9) in serum from patients with Werner syndrome (WS) and healthy individuals. Elevation of …

… Werner syndrome (MIM#277700) Individuals with Werner syndrome do well until puberty
when decreased growth and hypogonadism become apparent. Greying of hair typically starts …