… mutation analysis. We present the first reported case of meningioma in a patient with Werner
syndrome and a confirmed major mutation. … meningioma associated with Werner syndrome. …

… Lines represent the different predicted truncated proteins produced from mutations in the
WRN gene. Mutation Analysis Mutations were detected by amplifying WRN exons from …

… the pheno typic expression of Werner syndrome features in homozy gotes … mutations in the
protein, we characterized the mutations in the WRN gene in a Caucasian family with Werner …

… Samples were collected from individuals with Werner syndrome participating in our International
Registry of Werner Syndrome (www.wernersyndrome.org), supplemented by materials …

The correlation between mutations in the Werner’s syndrome (WRN) gene and the
haplotypes of surrounding markers was studied in Japanese patients. We have elucidated the …

… Werner syndrome (WS) is a rare autosomal recessive progeroid disorder. The Werner syndrome
… Four distinct mutations were previously reported in three Japanese and one Syrian WS …

… Prevalence of Werner syndrome gene mutations in the Japanese population: A genetic
epidemiological study. In: Gann Monograph on Cancer Research No.49. From premature gray …

… syndromes. One prominent example is our work to better define patients with “atypical Werner
syndrome (… , but were found on subsequent analysis to lack WRN mutations. As of 2015, …

… Mutation and haplotype analyses of the Werner’s syndrome gene based on its genomic
structure: genetic epidemiology in the Japanese population. Hum Genet. 1997;100(1):123– 130. …

… mutations was studied in 89 Japanese Werner’s syndrome (WRN) patients by examining the
previously described mutations 1– 4 as well as a new mutation … the Werner syndrome gene …