Adrenocorticotropic hormone for the treatment of West Syndrome in children

NA Shumiloff, WM Lam… - Annals of …, 2013 - journals.sagepub.com
… , West syndrome, adrenocorticotropic hormone, corticotropin, symptomatic West syndrome,
cryptogenic West syndrome, … use of ACTH for infantile spasms or West syndrome in pediatric …

… efficacy and adverse effects of adrenocorticotropic hormone therapy in west syndrome: differences in dosage of adrenocorticotropic hormone, onset of age, and cause

S Hamano, S Yamashita, M Tanaka, S Yoshinari… - The Journal of …, 2006 - Elsevier
… Ito et al 2 documented that lower-dose ACTH therapy was as effective to control spasms …
West syndrome treated with ACTH therapy to evaluate the efficacy and adverse effects of ACTH

Cardiac vagal activation by adrenocorticotropic hormone treatment in infants with West syndrome

A Hattori, J Hayano, S Fujimoto, N Ando… - The Tohoku journal of …, 2007 - jstage.jst.go.jp
… These results indicate that West syndrome might be accompanied by autonomic changes
and that ACTH treatment enhances parasympathetic function and causes bradycardia. ───…

Efficacy of long‐term adrenocorticotropic hormone therapy for West syndrome: a retrospective multicenter case series

S Baba, T Okanishi, Y Homma, T Yoshida… - Epilepsia …, 2021 - Wiley Online Library
adrenocorticotropic hormone (ACTH) and subsequent months of weekly injections, was tried
for relapsed West syndrome (… Our aim was to explore the efficacy of LT-ACTH for preventing …

How do the many etiologies of West syndrome lead to excitability and seizures? The corticotropin releasing hormone excess hypothesis

KL Brunson, M Eghbal-Ahmadi, TZ Baram - Brain and Development, 2001 - Elsevier
West syndrome (WS) is associated with diverse etiological factors. This fact has suggested
… to treatment by a hormone, ACTH? The established hormonal role of ACTH in human …

Serial analysis of multiple serum cytokine responses to adrenocorticotropic hormone therapy in patients with West syndrome

G Yamanaka, N Morishita, S Morichi… - Journal of Child …, 2018 - journals.sagepub.com
… ) therapy is effective for West syndrome; however, the … West syndrome, injected with ACTH
for 28 days. Serum samples were obtained before and 30, 120, and 720 minutes after ACTH

Decreased abundance of Akkermansia after adrenocorticotropic hormone therapy in patients with West syndrome

L Xu, D Chen, C Zhao, L Jiang, S Mao, C Song, F Gao - BMC microbiology, 2021 - Springer
… Infants suffer from a severe epileptic encephalopathy known as West syndrome (WS).
Treatment with adrenocorticotropic hormone (ACTH) indicates the involvement of the gut-brain …

Reduction in glutamine/glutamate levels in the cerebral cortex after adrenocorticotropic hormone therapy in patients with west syndrome

M Munakata, N Togashi, O Sakamoto… - The Tohoku Journal of …, 2014 - jstage.jst.go.jp
West syndrome (WS), an intractable epileptic encephalopathy of … , adrenocorticotropic
hormone (ACTH) is an effective treatment for WS. The mechanism behind the efficacy of ACTH is …

Response and Outcome of Moderate Dose Adrenocorticotropic Hormone in the Treatment of West Syndrome

M Chandra, N Saha, PK Sarkar, MSN Sumi… - Journal of National …, 2021 - banglajol.info
… Results of the study documented that moderate dose ACTH is found to be effective in cessation
of spasm and resolution of hypsarrhythmia in the studied children of west syndrome. The …

Predictive factors for relapse of epileptic spasms after adrenocorticotropic hormone therapy in West syndrome

Y Hayashi, H Yoshinaga, T Akiyama, F Endoh… - Brain and …, 2016 - Elsevier
West syndrome (WS) is an age-dependent epileptic encephalopathy that causes …
Adrenocorticotropic hormone (ACTH) therapy is considered the most effective therapy for WS, and its …