A comparative study of high-dose and low-dose ACTH therapy for West syndrome

S Yanagaki, H Oguni, K Hayashi, K Imai… - Brain and …, 1999 - Elsevier
… effective ACTH dose, with the fewest adverse effects, for the treatment of West syndrome (WS). …
There were no significant differences in initial responses between the low-dose and high-…

West syndrome: a review and guide for paediatricians

R D'Alonzo, D Rigante, E Mencaroni… - Clinical drug …, 2018 - Springer
doses are as effective as high doses for short-term treatment, which is generally 2 weeks
followed by dose … ACTH dosage groups and demonstrated no significant differences in the …

Therapeutic efficacy and adverse effects of adrenocorticotropic hormone therapy in west syndrome: differences in dosage of adrenocorticotropic hormone, onset of …

S Hamano, S Yamashita, M Tanaka, S Yoshinari… - The Journal of …, 2006 - Elsevier
… In our study, there were no differences in efficacy among various dosages. This … West
syndrome. This also showed that the severity of adverse effects correlated with the ACTH dosage, …

West syndrome: a comprehensive review

P Pavone, A Polizzi, SD Marino, G Corsello… - Neurological …, 2020 - Springer
… our search the MeSH term “West syndrome” vs. “infantile spasm syndrome”, the results were
more … term West syndrome is still more incardinated and most widely used in the literature. …

Comparison of two low dose ACTH therapies for West syndrome: their efficacy and side effect

Y Kondo, A Okumura, K Watanabe, T Negoro… - Brain and …, 2005 - Elsevier
… A), and 0.010mg/kg/dose in 16 patients who were … dose of ACTH until cessation of spasms
were significantly smaller in regimen A than in regimen B. There was no significant difference

The treatment of West syndrome: a Cochrane review of the literature to December 2000

E Hancock, JP Osborne, P Milner - Brain and Development, 2001 - Elsevier
… We also looked for subgroup analysis of clinical features, for example; developmental delay
prior to onset of spasms, differences in drug dosages, timing and length of treatment and …

A comparative study of conventional dose and low dose adrenocorticotrophic hormone therapy for West syndrome

XM Shu, J Li, GP Zhang, Q Mao - Zhongguo Dang dai er ke za zhi …, 2009 - europepmc.org
differences in the good initial responses between the conventional and the low dose
groups, … 8 responders, and there were no significant differences between the two groups (follow-up …

Adrenocorticotropic hormone for the treatment of West Syndrome in children

NA Shumiloff, WM Lam… - Annals of …, 2013 - journals.sagepub.com
… - versus high-dose ACTH regimens, low-dose ACTH regimens, and … or vigabatrin for the
treatment of West syndrome. … were no significant differences between low- and high-dose ACTH …

Zonisamide for West syndrome: a comparison of clinical responses among different titration rate

S Yanagaki, H Oguni, K Yoshii, K Hayashi, K Imai… - Brain and …, 2005 - Elsevier
… Most of the authors gave ZNS to patients with West syndrome by a rapid stepwise increase
of dosage from 3 to 9–13 mg/kg every 3–4 days. However, it would take 2–3 weeks for the …

Treatment of West syndrome

Y Sakakihara - Brain and Development, 2011 - Elsevier
… different dosing schedules for ACTH therapy [9]. As for alternate regimens, he briefly
mentioned high dose valproate therapy and vigabatrin for West syndrome with tuberous sclerosis. …