[HTML][HTML] Wnt/β-catenin signaling: components, mechanisms, and diseases
BT MacDonald, K Tamai, X He - Developmental cell, 2009 - cell.com
… -catenin destruction complex, and nuclear machinery that mediates β-catenin-dependent
transcription. Finally, we highlight some key aspects of Wnt/β-catenin signaling in human …
transcription. Finally, we highlight some key aspects of Wnt/β-catenin signaling in human …
Wnt/β-catenin signaling
T Akiyama - Cytokine & growth factor reviews, 2000 - Elsevier
The Wnt/Wingless signaling … β-Catenin, a key component of the Wnt signaling pathway,
interacts with the TCF/LEF family of transcription factors and activates transcription of Wnt target …
interacts with the TCF/LEF family of transcription factors and activates transcription of Wnt target …
[HTML][HTML] Wnt/β-catenin signaling and disease
… In parallel, aberrant Wnt signaling underlies a wide range of pathologies in humans. In this
Review, we provide an update of the core Wnt/β-catenin signaling pathway, discuss how its …
Review, we provide an update of the core Wnt/β-catenin signaling pathway, discuss how its …
[HTML][HTML] Wnt/β-catenin signaling in development and disease
H Clevers - Cell, 2006 - cell.com
… the canonical Wnt/β-catenin signaling pathway. Another tyrosine kinase receptor, Ror2,
harbors a Wnt binding CRD motif. Wnt5a can engage Ror2 to inhibit the canonical Wnt signaling …
harbors a Wnt binding CRD motif. Wnt5a can engage Ror2 to inhibit the canonical Wnt signaling …
[HTML][HTML] Wnt–β-catenin signaling
KM Cadigan - Current Biology, 2008 - cell.com
… While the number of identified potential Wnt receptors is growing, it is also clear that most
Wnt–β-catenin signaling occurs through an unlikely pairing of members of two distinct receptor …
Wnt–β-catenin signaling occurs through an unlikely pairing of members of two distinct receptor …
SnapShot: Wnt/β-catenin signaling
BT MacDonald, MV Semenov, X He - Cell, 2007 - cell.com
… RTK signaling phosphorylates cadherin-bound β-catenin at Y142 and Y654, via RTK … β-catenin
from cadherin, resulting in an increase in cytosolic β-catenin and TCF/β-catenin signaling…
from cadherin, resulting in an increase in cytosolic β-catenin and TCF/β-catenin signaling…
[HTML][HTML] Wnt/β-catenin signaling, disease, and emerging therapeutic modalities
… Unsurprisingly, mutated Wnt pathway components are … core Wnt/β-catenin signaling pathway,
how it controls stem cells, and contributes to disease. Finally, we discuss strategies for Wnt-…
how it controls stem cells, and contributes to disease. Finally, we discuss strategies for Wnt-…
Wnt/β-catenin signaling: new (and old) players and new insights
H Huang, X He - Current opinion in cell biology, 2008 - Elsevier
… Therefore the study of Wnt/β-catenin signaling not only … of β-catenin degradation complex
and Wnt receptor activation. For a more comprehensive discussion on Wnt/β-catenin signaling …
and Wnt receptor activation. For a more comprehensive discussion on Wnt/β-catenin signaling …
On the role of Wnt/β-catenin signaling in stem cells
SJ Kühl, M Kühl - Biochimica et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
… Here we summarize our current knowledge on the role of Wnt/β-catenin signaling with …
linked to Wnt/β-catenin signaling. Other substances interfere with TCF/LEF/β-catenin complex …
linked to Wnt/β-catenin signaling. Other substances interfere with TCF/LEF/β-catenin complex …
[HTML][HTML] Targeting the Wnt/β-catenin signaling pathway in cancer
Y Zhang, X Wang - Journal of hematology & oncology, 2020 - Springer
… Collectively, underscoring the physiological importance of Wnt/β-catenin signaling pathway
in … the advances and challenges of Wnt/β-catenin signaling pathway targeted interventions in …
in … the advances and challenges of Wnt/β-catenin signaling pathway targeted interventions in …
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