Wnt signaling and the control of human stem cell fate

JK Van Camp, S Beckers, D Zegers… - … Cell Reviews and Reports, 2014 - Springer
… and independent Wnt pathways exist, and both affect stem cell fate in developing and adult
… the response to Wnt signal activation in embryonic stem cells and human, adult stem cells of …

Wnt signaling in hematopoiesis: crucial factors for self‐renewal, proliferation, and cell fate decisions

FJT Staal, TC Luis - Journal of cellular biochemistry, 2010 - Wiley Online Library
… Our own work has shown that while in the thymus Wnt signaling provides … Wnt signaling
in HSC regulates cell fate decisions, in particular self-renewal versus differentiation. J. Cell. …

Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision

T Nakamura, K Tsuchiya, M Watanabe - Journal of gastroenterology, 2007 - Springer
Wnt and Notch pathways control intestinal epithelial cell fate decisions, particularly focusing
on their crosstalk at both tissue and cellular … in the cell fate decision, and the Wnt signal is …

[HTML][HTML] Canonical Wnt signaling dynamically controls multiple stem cell fate decisions during vertebrate body formation

BL Martin, D Kimelman - Developmental cell, 2012 - cell.com
… stem cell, allowing the embryo to dynamically allocate cell fates as the body … Wnt signaling
has a role in regulating a second fate decision between somite and posterior vascular fates

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

AS Brack, MJ Conboy, S Roy, M Lee, CJ Kuo, C Keller… - Science, 2007 - science.org
… When incubated with Frizzled-Fc, the activity in aged serum that promoted Wnt signaling
We altered Wnt signaling experimentally to test directly for its effects on cell fate and muscle …

[HTML][HTML] Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells

K Vijayaragavan, E Szabo, M Bossé, V Ramos-Mejia… - Cell stem cell, 2009 - cell.com
… of cells committed to a cell fate are poorly understood. We demonstrate that activation of
canonical Wnt signaling by Wnt3a promotes proliferation of human embryonic stem cells (hESCs…

WNT signaling and chondrocytes: from cell fate determination to osteoarthritis physiopathology

N Sassi, L Laadhar, M Allouche, A Achek… - … Receptors and Signal …, 2014 - Taylor & Francis
WNT signaling constitutes one of the most critical biological processes during cell fate … the
studies that were interested in the involvement of WNT in OA. Methods: Studies were selected …

WNTs modulate cell fate and behavior during vertebrate development

RT Moon, JD Brown, M Torres - Trends in genetics, 1997 - cell.com
… is a conserved and important aspect of specifying neural ceil fate and function. WNT signaling
might also play a general role in specification of neural cell fate along the anteroposterior …

[HTML][HTML] An evolutionary conserved role of Wnt signaling in stem cell fate decision

R Teo, F Möhrlen, G Plickert, WA Müller, U Frank - Developmental biology, 2006 - Elsevier
… A role for Wnt signaling in invertebrate stem cells is so far … of stem cell fate was an additional
function Wnt proteins adopted … role of the canonical Wnt signaling pathway on stem cell fate

[HTML][HTML] Regulation of stem cell proliferation and cell fate specification by Wingless/Wnt signaling gradients enriched at adult intestinal compartment boundaries

A Tian, H Benchabane, Z Wang, Y Ahmed - PLoS genetics, 2016 - journals.plos.org
… JAK-STAT signaling in neighboring … signaling is required for proper cell fate specification
near compartment boundaries during development. We conclude that gradients of Wg signaling