YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage
A Elbediwy, ZI Vincent‐Mistiaen, BJ Thompson - Bioessays, 2016 - Wiley Online Library
… We then examine the regulation of YAP and TAZ in different mammalian epithelial tissues in
… of YAP and TAZ during human epithelial cancer progression, where disruption of cell polarity…
… of YAP and TAZ during human epithelial cancer progression, where disruption of cell polarity…
YAP/TAZ functions and their regulation at a glance
A Pocaterra, P Romani, S Dupont - Journal of cell science, 2020 - journals.biologists.com
… YAP/TAZ is the formation of cell–cell contacts (both adherens and tight junctions) and the
resulting establishment of apicobasal cell polarity… between cell polarity and YAP/TAZ is far from …
resulting establishment of apicobasal cell polarity… between cell polarity and YAP/TAZ is far from …
[HTML][HTML] Dual function of Yap in the regulation of lens progenitor cells and cellular polarity
JY Song, R Park, JY Kim, L Hughes, L Lu, S Kim… - Developmental …, 2014 - Elsevier
… In summary, Yap proteins colocalize with Crb polarity complex … that Yap is essential for the
proper organization of the lens cells by … the link between cell-to-cell contact and TAZ, a closely …
proper organization of the lens cells by … the link between cell-to-cell contact and TAZ, a closely …
Molecular pathways: YAP and TAZ take center stage in organ growth and tumorigenesis
S Piccolo, M Cordenonsi, S Dupont - Clinical cancer research, 2013 - AACR
… Critical elements of such a suppressive microenvironment are structural characteristics of
normal cells and tissues, such as cell polarity, attachment to the extracellular matrix (ECM), …
normal cells and tissues, such as cell polarity, attachment to the extracellular matrix (ECM), …
[HTML][HTML] Distinct polarity cues direct Taz/Yap and TGFβ receptor localization to differentially control TGFβ-induced Smad signaling
M Narimatsu, P Samavarchi-Tehrani, X Varelas… - Developmental Cell, 2015 - cell.com
… TAZ and YAP (TAZ/YAP) interact with Smads and control TGFβ-regulated Smad activity. Our
work showed that TAZ and YAP … epithelial cell polarity cues can be uncoupled from Taz/Yap, …
work showed that TAZ and YAP … epithelial cell polarity cues can be uncoupled from Taz/Yap, …
An overview of signaling pathways regulating YAP/TAZ activity
BC Heng, X Zhang, D Aubel, Y Bai, X Li, Y Wei… - Cellular and Molecular …, 2021 - Springer
… polarity complexes through the Hippo signaling pathway Cell polarity is a distinctive feature
of various cell … Membrane protein complexes that play key roles in cell polarity include aPKC-…
of various cell … Membrane protein complexes that play key roles in cell polarity include aPKC-…
Control of stem cell renewal and fate by YAP and TAZ
JH Driskill, D Pan - Nature Reviews Molecular Cell Biology, 2023 - nature.com
… In this Review, we discuss how YAP/TAZ control stem cell fate … by which YAP/TAZ mediate
stem cell decisions between … , YAP/TAZ, controlled by cell–cell contact and cell polarity, …
stem cell decisions between … , YAP/TAZ, controlled by cell–cell contact and cell polarity, …
The biology of YAP/TAZ: hippo signaling and beyond
S Piccolo, S Dupont, M Cordenonsi - Physiological reviews, 2014 - journals.physiology.org
… of YAP/TAZ and their regulation in mammalian cells, where Hippo regulations blend with
forms of YAP/TAZ … to membrane localization of Scribble, a key cell polarity determinant. At the …
forms of YAP/TAZ … to membrane localization of Scribble, a key cell polarity determinant. At the …
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
… to TAZ, and probably YAP, activity. In addition, matrix stiffness … cell polarity 37,75 , which is
a key factor regulating TAZ stability in breast cancer. TAZ forms a complex with the cell-polarity …
a key factor regulating TAZ stability in breast cancer. TAZ forms a complex with the cell-polarity …
Regulation of YAP/TAZ activity by mechanical cues: an experimental overview
S Dupont - The Hippo Pathway: Methods and Protocols, 2019 - Springer
… YAP/TAZ activity is regulated by a complex network of signals that include the Hippo pathway,
cell polarity complexes, and signaling receptors of the RTK, GPCR, and WNT pathways …
cell polarity complexes, and signaling receptors of the RTK, GPCR, and WNT pathways …
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