… We then examine the regulation of YAP and TAZ in different mammalian epithelial tissues in
… of YAP and TAZ during human epithelial cancer progression, where disruption of cell polarity…

… YAP/TAZ is the formation of cell–cell contacts (both adherens and tight junctions) and the
resulting establishment of apicobasal cell polarity… between cell polarity and YAP/TAZ is far from …

… In summary, Yap proteins colocalize with Crb polarity complex … that Yap is essential for the
proper organization of the lens cells by … the link between cell-to-cell contact and TAZ, a closely …

… Critical elements of such a suppressive microenvironment are structural characteristics of
normal cells and tissues, such as cell polarity, attachment to the extracellular matrix (ECM), …

… TAZ and YAP (TAZ/YAP) interact with Smads and control TGFβ-regulated Smad activity. Our
work showed that TAZ and YAP … epithelial cell polarity cues can be uncoupled from Taz/Yap, …

… polarity complexes through the Hippo signaling pathway Cell polarity is a distinctive feature
of various cell … Membrane protein complexes that play key roles in cell polarity include aPKC-…

… In this Review, we discuss how YAP/TAZ control stem cell fate … by which YAP/TAZ mediate
stem cell decisions between … , YAP/TAZ, controlled by cell–cell contact and cell polarity, …

… of YAP/TAZ and their regulation in mammalian cells, where Hippo regulations blend with
forms of YAP/TAZ … to membrane localization of Scribble, a key cell polarity determinant. At the …

… to TAZ, and probably YAP, activity. In addition, matrix stiffness … cell polarity 37,75 , which is
a key factor regulating TAZ stability in breast cancer. TAZ forms a complex with the cell-polarity …

… YAP/TAZ activity is regulated by a complex network of signals that include the Hippo pathway,
cell polarity complexes, and signaling receptors of the RTK, GPCR, and WNT pathways …