… we discuss how YAP/TAZ control stem cell fate … YAP/TAZ mediate stem cell decisions
between renewal and fate. We systematically analyse the role of YAP/TAZ from totipotent stem cells …

… Yet, how YAP and TAZ are physiologically regulated remains unclear. Here we review …
that YAP and TAZ act primarily as sensors of epithelial cell polarity, being inhibited when cells …

… Thus, the shift from TAZ into YAP expression upregulated cancer stem cell markers, such
as CD90 and CD13, and conferred cancer stem cell–like properties represented by …

… Stem cells and cancer are relevant systems for this undertaking, … on how YAP and TAZ
regulate cell fate in stem cells and … Functions of YAP in embryogenesis, stem cell fate and …

… Elevated YAP protein levels and gene amplification have … we report that YAP is inactivated
during embryonic stem (ES) cell … , both YAP and TAZ are new factors that contribute to ES cell …

… We propose that TAZ, as well as a highly related molecule YAP, are functionally, though
not structurally, similar to β-catenin and integrate extracellular, membrane, and cytoskeletal-…

… In the case of bone marrow-derived mesenchymal stem cells (BMSCs), increased YAP/TAZ
activation on a stiff substrate leads to enhancement of osteogenic differentiation [11]. …

… proliferation, as YAP and TAZ translocation from … YAP and TAZ nuclear import with verteporfin,
a small-molecule inhibitor of YAP and TAZ, which up-regulates 14-3-3σ to sequester YAP …

… mechanical signals regulate YAP/TAZ activity in stem cells is not … of the mechanisms involved
in YAP/TAZ regulation on the … /Slug-YAP/TAZ complex to control stem cell function (65). …

… YAP and TAZ mechanobiology in embryonic stem cells. YAP and TAZ and their regulation
by cell mechanics control the first cell fate decision in the mammalian embryo, namely, the …