YB1 protein: functions and regulation

DN Lyabin, IA Eliseeva… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
… For example, during specific mRNA stabilization, YB-1 acts together with one (eg, PTB in …
YB-1 mRNA and other mRNAs are similar. Inhibition of YB-1 mRNA translation at lower YB-1

[HTML][HTML] The major mRNA‐associated protein YB1 is a potent 5′ cap‐dependent mRNA stabilizer

V Evdokimova, P Ruzanov, H Imataka, B Raught… - The EMBO …, 2001 - embopress.org
… for YB1‐mediated mRNA stabilization (Figure 2B), we next analyzed whether mRNA
stabilization by YB1 is … To assess the role of the cap in YB1‐mediated mRNA stabilization, …

Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation

CY Chen, R Gherzi, JS Andersen… - Genes & …, 2000 - genesdev.cshlp.org
… nucleolin and YB-1 specifically associate with IL-2 mRNA in … for JNK-mediated IL-2 mRNA
stabilization. On the basis of a … of IL-2 mRNA is associated with nucleolin and YB-1 (data not …

Structural organization of mRNA complexes with major core mRNP protein YB-1

MA Skabkin, OI Kiselyova, KG Chernov… - Nucleic acids …, 2004 - academic.oup.com
mRNA, YB-1 stimulates or inhibits mRNA translation. In this study, we have analyzed complexes
formed in vitro at various YB-1 to mRNA … shown that at mRNA saturation with YB-1, this …

The formation of HuR/YB1 complex is required for the stabilization of target mRNA to promote myogenesis

BJ Sánchez, S Mubaid, S Busque… - Nucleic Acids …, 2023 - academic.oup.com
… /YB1 binding motif extends beyond muscle cells. We also show that the HuR/YB1 complex
is required for the stabilization of mRNA … HuR and YB1 may constitute a stabilizing complex …

mRNA and DNA selection via protein multimerization: YB-1 as a case study

DA Kretov, PA Curmi, L Hamon, S Abrakhi… - Nucleic acids …, 2015 - academic.oup.com
… As a proof of concept of this model, we show that the cooperative binding of YB-1 to mRNA
stabilizes saturated YB-1:mRNA complexes (Figure 4C). In addition, after mixing saturated …

Y-box binding proteins in mRNP assembly, translation, and stability control

D Mordovkina, DN Lyabin, EA Smolin, EM Sogorina… - Biomolecules, 2020 - mdpi.com
YB proteins in RNA-dependent processes, such as mRNA packaging into mRNPs, mRNA
translation, and mRNA stabilization… In addition, recent data on the structural peculiarities of YB

Expression of YB-1 enhances production of murine leukemia virus vectors by stabilizing genomic viral RNA

W Li, X Wang, G Gao - Protein & cell, 2012 - academic.oup.com
… the R region as a responsive element to YB-1-mediated specific stabilization (Fig. 4). …
YB-1-mediated stabilization of specific mRNAs. In conclusion, we identified YB-1 as a MLV mRNA

Towards the mechanism (s) of YB-3 synthesis regulation by YB-1

DN Lyabin, EA Smolin, KS Budkina, IA Eliseeva… - RNA biology, 2021 - Taylor & Francis
YB-1 participates in the translational control and stabilization of YB-3 mRNA through untranslated
regions of YB-3 mRNA. … that YB-1 is involved in translational control and stabilization of …

YB-1 stabilizes HIV-1 genomic RNA and enhances viral production

X Mu, W Li, X Wang, G Gao - Protein & cell, 2013 - Springer
… transcription or mRNA stabilization. To test whether YB-1 enhances HIV-1 transcription in …
firefly luciferase gene transcription is driven by HIV-1 LTR (U3, R and U5). Data show that …