[HTML][HTML] The major mRNA‐associated protein YB1 is a potent 5′ cap‐dependent mRNA stabilizer

V Evdokimova, P Ruzanov, H Imataka, B Raught… - The EMBO …, 2001 - embopress.org
… for YB1‐mediated mRNA stabilization (Figure 2B), we next analyzed whether mRNA
stabilization by YB1 is … To assess the role of the cap in YB1‐mediated mRNA stabilization, …

YB1 protein: functions and regulation

DN Lyabin, IA Eliseeva… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
… of YB-1 studies was focused on its role in regulation of mRNA translation and in mRNA
packaging and stabilization. … For example, during specific mRNA stabilization, YB-1 acts together …

Structural organization of mRNA complexes with major core mRNP protein YB-1

MA Skabkin, OI Kiselyova, KG Chernov… - Nucleic acids …, 2004 - academic.oup.com
mRNA, YB-1 stimulates or inhibits mRNA translation. In this study, we have analyzed complexes
formed in vitro at various YB-1 to mRNA … shown that at mRNA saturation with YB-1, this …

Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation

CY Chen, R Gherzi, JS Andersen… - Genes & …, 2000 - genesdev.cshlp.org
… We next examined whether nucleolin or YB-1 are involved in stabilization of IL-2 mRNA
in vivo. As YB-1 and nucleolin are relatively abundant and ubiquitous proteins, we chose to …

The formation of HuR/YB1 complex is required for the stabilization of target mRNA to promote myogenesis

BJ Sánchez, S Mubaid, S Busque… - Nucleic Acids …, 2023 - academic.oup.com
… /YB1 binding motif extends beyond muscle cells. We also show that the HuR/YB1 complex
is required for the stabilization of mRNA … HuR and YB1 may constitute a stabilizing complex …

Expression of YB-1 enhances production of murine leukemia virus vectors by stabilizing genomic viral RNA

W Li, X Wang, G Gao - Protein & cell, 2012 - academic.oup.com
… the R region as a responsive element to YB-1-mediated specific stabilization (Fig. 4). …
YB-1-mediated stabilization of specific mRNAs. In conclusion, we identified YB-1 as a MLV mRNA

Towards the mechanism (s) of YB-3 synthesis regulation by YB-1

DN Lyabin, EA Smolin, KS Budkina, IA Eliseeva… - RNA biology, 2021 - Taylor & Francis
YB-1 participates in the translational control and stabilization of YB-3 mRNA through untranslated
regions of YB-3 mRNA. … that YB-1 is involved in translational control and stabilization of …

[HTML][HTML] Y-box binding proteins in mRNP assembly, translation, and stability control

D Mordovkina, DN Lyabin, EA Smolin, EM Sogorina… - Biomolecules, 2020 - mdpi.com
YB proteins in RNA-dependent processes, such as mRNA packaging into mRNPs, mRNA
translation, and mRNA stabilization… In addition, recent data on the structural peculiarities of YB

Y box-binding factor promotes eosinophil survival by stabilizing granulocyte-macrophage colony-stimulating factor mRNA

EE Capowski, S Esnault, S Bhattacharya… - The Journal of …, 2001 - journals.aai.org
… indicate that YB-1 interacts with the GM-CSF mRNA through … GM-CSF mRNA
coimmunoprecipitates with endogenous YB-1 … leads to YB-1 binding to and stabilization of …

YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

DA Kretov, MJ Clément, G Lambert… - Nucleic acids …, 2019 - academic.oup.com
… This, to our knowledge, is the first mRNA-binding protein capable to stabilize RNA in a
linear conformation. The formation of a nucleoprotein filament relies on an electrostatic zipper …