Regulation of ZEB1 function and molecular associations in tumor progression and metastasis
M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
… of ZEB1 in mediating tumor progression and metastasis and describe the ways in which protein
modifications can regulate its molecular associations and function… regulation of ZEB1′s …
modifications can regulate its molecular associations and function… regulation of ZEB1′s …
[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications
Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
… ZEB1 … ZEB1 and these chromatin-modifying enzymes may represent an efficient for treating
cancer. In this review, we outlined the biological function of ZEB1 in tumorigenic progression …
cancer. In this review, we outlined the biological function of ZEB1 in tumorigenic progression …
[HTML][HTML] Expanding roles of ZEB factors in tumorigenesis and tumor progression
E Sánchez-Tilló, L Siles, O De Barrios… - American journal of …, 2011 - ncbi.nlm.nih.gov
… Evidence in the literature indicates that ZEB1 and ZEB2 play … its tumor progression role
discussed so far, ZEB1 inhibits tumor … to larger tumors with more tumor vessels—and higher ZEB1 …
discussed so far, ZEB1 inhibits tumor … to larger tumors with more tumor vessels—and higher ZEB1 …
Pleiotropic roles for ZEB1 in cancer
J Caramel, M Ligier, A Puisieux - Cancer research, 2018 - AACR
… ZEB1 is a prime element of a network of transcription factors … Aberrant expression of ZEB1
has been reported in a variety … unsuspected intrinsic oncogenic functions of ZEB1 that impact …
has been reported in a variety … unsuspected intrinsic oncogenic functions of ZEB1 that impact …
[HTML][HTML] The curious case of ZEB1
M Madany, T Thomas, LA Edwards - Discoveries, 2018 - ncbi.nlm.nih.gov
… In vivo studies 38 have shown that tumors with increased ZEB1 and lowered E-Cadherin …
cementing the role of ZEB1 in EMT and tumor progression. This role of ZEB1 has been further …
cementing the role of ZEB1 in EMT and tumor progression. This role of ZEB1 has been further …
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
O Schmalhofer, S Brabletz, T Brabletz - Cancer and Metastasis Reviews, 2009 - Springer
… In this context, ZEB1-mediated loss of the basement membrane contributes to tumor progression
and disturbance of tissue architecture in a dual fashion: by loosing a mechanical barrier …
and disturbance of tissue architecture in a dual fashion: by loosing a mechanical barrier …
Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies
R Fu, Y Li, N Jiang, BX Ren, CZ Zang… - The Journal of …, 2020 - Am Soc Clin Investig
… of vascular ZEB1 in tumor progression, we evaluated LLC and B16F10 tumor models by
subcutaneous implantation of LLC and B16F10 cells into 9-week-old Zeb1 WT and Zeb1 iΔEC …
subcutaneous implantation of LLC and B16F10 cells into 9-week-old Zeb1 WT and Zeb1 iΔEC …
ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
… mechanisms by which ZEB1 regulates tumor progression and treatment resistance. Based
on studies by us and others, we propose that it is specific EMT inducers like ZEB1, but not the …
on studies by us and others, we propose that it is specific EMT inducers like ZEB1, but not the …
Tumor‐associated macrophages (TAMs) depend on ZEB1 for their cancer‐promoting roles
M Cortés, L Sanchez‐Moral, O de Barrios… - The EMBO …, 2017 - embopress.org
… We then turned to investigate the molecular mechanisms by which the expression of ZEB1
in TAMs promotes an enhanced tumor progression in the ID8 cancer model. The CCL2-CCR2 …
in TAMs promotes an enhanced tumor progression in the ID8 cancer model. The CCL2-CCR2 …
ZEB1: New advances in fibrosis and cancer
L Cheng, MY Zhou, YJ Gu, L Chen, Y Wang - Molecular and Cellular …, 2021 - Springer
… structure of ZEB1 and the protein binding sites of ZEB1 with some … roles of ZEB1 in fibrosis
and cancer progression to elaborate … , ZEB1 facilitates tumor progression and promotes tumor …
and cancer progression to elaborate … , ZEB1 facilitates tumor progression and promotes tumor …