[HTML][HTML] ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM

Y Zhou, F Lin, T Wan, A Chen, H Wang, B Jiang… - Theranostics, 2021 - ncbi.nlm.nih.gov
… To answer whether ZEB1-PFKM axis contributes to tumor progression in vivo, we performed
in vivo tumor formation experiment by injecting MHCC-97H cells into the same site of the left …

[HTML][HTML] LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process

Z Sun, B Shao, Z Liu, Q Dang, Y Guo, C Chen… - Journal of …, 2021 - ncbi.nlm.nih.gov
… In recent years, some studies confirmed that long non-coding RNA (lncRNA) played an
essential role in tumor progression. A few studies reported that LINC01296 acted as an …

[HTML][HTML] ZEB1 transcription factor promotes immune escape in melanoma

M Plaschka, V Benboubker, M Grimont… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
ZEB1 gain-of-function or loss-of-function approaches were … models, followed by monitoring
of tumor growth, quantification of … focused on ZEB1, given its prominent oncogenic function in …

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

T Kim, A Veronese, F Pichiorri, TJ Lee… - Journal of Experimental …, 2011 - rupress.org
… process in tumor progression and metastasis. The transcription factors ZEB1 and ZEB2
promote EMT. Here, we show that p53 suppresses EMT by repressing expression of ZEB1 and …

LincRNA-ROR promotes invasion, metastasis and tumor growth in pancreatic cancer through activating ZEB1 pathway

H Zhan, Y Wang, C Li, J Xu, B Zhou, J Zhu, H Han… - Cancer letters, 2016 - Elsevier
… and analyzed ZEB1, and p53 expression using qRT-PCR. We found that linc-ROR
expression is positively correlated with ZEB1 (Fig. 8A), while linc-ROR and ZEB1 expression is …

[HTML][HTML] ZEB1-AS1 initiates a miRNA-mediated ceRNA network to facilitate gastric cancer progression

MH Ma, JX An, C Zhang, J Liu, Y Liang… - Cancer cell …, 2019 - Springer
… As long noncoding RNA ZEB1-AS1 has been reported to function as an oncogene due to
sponging microRNAs (miRNAs) in several cancers, we hypothesized that it could interact with …

[HTML][HTML] Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch

C Miro, E Di Cicco, R Ambrosio, G Mancino… - Nature …, 2019 - nature.com
… To gain insight into the role of TH in tumor progression, we disrupted the TH signal balance
by depleting D2 or D3 in the epidermal compartment. To this end, we crossed D3 fl/fl 18 or …

[HTML][HTML] Interplay between long noncoding RNA ZEB1-AS1 and miR-101/ZEB1 axis regulates proliferation and migration of colorectal cancer cells

WC Xiong, N Han, N Wu, KL Zhao, C Han… - American journal of …, 2018 - ncbi.nlm.nih.gov
ZEB1 to tumor progression has been studied in several human cancers [28-31]. Accumulating
evidence has suggested that ZEB1 … study, ZEB1 was directly targeted by tumor suppressor …

The role of the ZEB family of transcription factors in development and disease

C Vandewalle, F Van Roy, G Berx - Cellular and molecular life sciences, 2009 - Springer
ZEB1/δEF1 gene is strongly homologous to the ZEB2/SIP1 gene structure, although Zeb1 has
a … The precise role of activated NF-kB in tumor progression is, however, unknown. A recent …

[HTML][HTML] ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease

M Singh, NS Spoelstra, A Jean, E Howe, KC Torkko… - Modern …, 2008 - nature.com
… for ZEB1 in tumor progression, specifically, epithelial to mesenchymal transitions, has recently
been revealed. ZEB1 … We previously demonstrated that ZEB1 is confined to the stromal …