Low-level pyrene exposure causes cardiac toxicity in zebrafish (Danio rerio) embryos

Y Zhang, C Wang, L Huang, R Chen, Y Chen, Z Zuo - Aquatic toxicology, 2012 - Elsevier
… In the present study, a low-level pyrene exposure to the developing zebrafish hearts also
caused some representative cardiac defects, such as altered looping and string-like chambers …

[HTML][HTML] Mixture effects of oxygenated PAHs and benzo [a] pyrene on cardiovascular development and function in zebrafish embryos

V Cunha, C Vogs, F Le Bihanic, K Dreij - Environment International, 2020 - Elsevier
zebrafish embryo with focus on the cardiotoxicity of these compounds. To this end,
developmental and cardiovascular toxicities were assessed in zebrafish embryos exposed to single …

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
… BaP exposure in humans and animals has been linked to infertility and … in zebrafish embryos
and larvae following a parental and continued embryonic waterborne BaP exposure. A total …

Transcriptomic changes in zebrafish embryos and larvae following benzo [a] pyrene exposure

X Fang, J Corrales, C Thornton, T Clerk… - Toxicological …, 2015 - academic.oup.com
… the embryos and larvae treated during the same BaP exposure. We found that parental and
early BaP exposure until … When the exposure continued until 96 hpf, we detected substantial …

Microplastic accumulation patterns and transfer of benzo [a] pyrene to adult zebrafish (Danio rerio) gills and zebrafish embryos

A Batel, F Borchert, H Reinwald, L Erdinger… - Environmental …, 2018 - Elsevier
zebrafish embryos after exposure to BaP-spiked microplastics. Furthermore, the gill EROD
(Ethoxyresorufin-O-deethylase) assay showed a clear trend to CYP 1A (Cytochrom P450 1 A) …

Benzo [a] pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos

L Huang, C Wang, Y Zhang, J Li, Y Zhong, Y Zhou… - Chemosphere, 2012 - Elsevier
… cardiac morphology and functioning of zebrafish embryos exposed to benzo[a]pyrene [B(a)P…
B(a)P exposure resulted in cardiac developmental defects in zebrafish embryos. Significant …

Developmental benzo [a] pyrene (B [a] P) exposure impacts larval behavior and impairs adult learning in zebrafish

AL Knecht, L Truong, MT Simonich… - Neurotoxicology and …, 2017 - Elsevier
… We exposed embryonic zebrafish to 0.4 and 4 μM B[a]P from 6 to 120 h post fertilization (hpf)
and evaluated behavioral changes at 120 hpf. Because B[a]P toxicity may not act …

Use of toxicogenomics to predict the potential toxic effect of benzo (a) pyrene on zebrafish embryos: ocular developmental toxicity

L Huang, Z Zuo, Y Zhang, M Wu, JJ Lin, C Wang - Chemosphere, 2014 - Elsevier
… In the present study, zebrafish embryos were exposed to BaP at concentrations of 0.02,
0.2 and 2 μM. These concentrations are within the range commonly used in laboratory …

Multigenerational effects of benzo [a] pyrene exposure on survival and developmental deformities in zebrafish larvae

J Corrales, C Thornton, M White, KL Willett - Aquatic toxicology, 2014 - Elsevier
… times as many zebrafish embryos were … embryos was undetected, the embryo exposure
may be most similar to lower PAH concentration exposures (waterborne or sediment) in embryos

[HTML][HTML] Integrated hypoxia signaling and oxidative stress in developmental neurotoxicity of benzo [a] pyrene in zebrafish embryos

YC Lin, CY Wu, CH Hu, TW Pai, YR Chen, WD Wang - Antioxidants, 2020 - mdpi.com
… In the positive control group, we exposed zebrafish embryos to 120 μM H 2 O 2 combined
with 0.1% DMSO and the embryonic levels of H 2 O 2 and lipid peroxidation in the embryos