… Schematic representation of hematopoiesis highlighting the participation of Zinc Finger
Proteins (ZNFs) in cell differentiation and/or maintenance. Hematopoietic Stem Cells (HSCs) give …

… The CCCH tandem zinc finger region in this family is characterized by 2 zinc … Given the
hematopoietic defects in the young mice, we examined hematopoiesis during development. We …

… Moz mutant fetal liver hematopoietic cells were incapable of contributing to the hematopoietic
system of recipients after transplantation. We observed profound defects in the stem cell …

… The protein MOZ (monocytic leukemia zinc finger protein) is … the generation and maintenance
of hematopoietic stem cells (HSC) … in normal and malignant hematopoiesis to elucidate the …

… toward hematopoiesis, we demonstrate that the defect is established at the earliest stage of
… Our results indicate that HAT −/− MOZ hematopoietic precursors display no substantial defect …

… in hematopoietic stem cells, we identified that Gfi-1B is preferentially expressed in hematopoietic
stem … To further understand the role of Gfi-1B in hematopoiesis, we used pseudo-type …

… value of targeting individual zinc fingers can be summarized as follows. First, the Ikzf1 ΔF1/ΔF1
and Ikzf1 ΔF4/ΔF4 mice exhibited select subsets of the hematopoietic defects of Ikzf1 null …

… We show here that a zinc finger transcriptional repressor, … antiapoptotic factor in normal
hematopoietic progenitor cells. Slug −/… in diverse subsets of hematopoietic progenitors, but not in …

… of hematopoietic cells. To assess the expression of Zfp521 throughout hematopoiesis, we
purified hematopoietic … Because Zfp521-dependent defects largely occur in the earliest T cell …

… Growing evidence indicates that zinc finger proteins regulate hematopoiesis, perhaps …
marked defect in hematopoietic development (59). Constitutive expression of the evi-1 zinc finger …