… and cytotoxic effect of Zoledronic acid on renal epithelial cells of monkey and dog kidney,
well-recommended models for studying the biological features of kidney cells. The information …

… To study and characterize the potential antitumoral effects of zoledronic acid (ZA) on renal
cancer cell … The human kidney carcinoma cell lines ACHN (ATCC number CRL-1611, “renal …

… A cell culture system of primary human tubular kidney cells has been developed in our
laboratory. The in vitro model was characterized extensively both at the physiological and …

… mechanism of zoledronic acid-related kidney damage was … of zoledronic acid and its potential
to induce cellular stresses … were examined in human embryonic kidney (HEK-293) cells. …

… kidney injury biomarkers compared to zoledronic acid, indicating that ibandronate induces
acute kidney … since ibandronate is less toxic than zoledronic acid. Our study suggests that the …

… , in rat kidneys. Using a normal (rat) kidney cell line NRK-52E, zoledronic acid inhibition
of FPPS activity was followed by a decrease in the level of prenylated protein and kidney cell …

… , keratinocytes, osteoblasts, adrenal cortex, intestinal epithelial, microglial cells and synovial
fibroblasts 23. It is constitutively expressed in the kidneys in the intercalated cells of the …

… Therefore, the behavior of kidney function during zoledronic acid treatment in the 30–59
GFR range and the possible impact of zoledronic acid on a change in GFR in this range are …

… group of patients treated with zoledronic acid 8 mg, the dose … Zoledronic acid is excreted
unchanged by the kidneys, partly … Most case reports are suggestive of tubular cell injury and, in …

Zoledronic acid (ZLD) is a bisphosphonate drug widely administered against pathological
conditions such as hypercalcemia of malignancy, osteoporosis, bone metastases from solid …