… Zoledronic acid enhances lipopolysaccharide-stimulated proinflammatory reactions through
… Cytokines and insulin resistance after zoledronic acid-induced acute phase response. …

… Hence, they are useful in detecting kidney damage sooner than creatinine and in several
clinical settings 11-14, 17, 25, 35-37. Hence, our cohort of osteoporosis patients with normal …

… zoledronic acid treatment. According to another authoritative source, the US … Kidney
Foundation Practice Guidelines for Chronic Kidney Disease, the prevalence rates of kidney damage …

… Zoledronic acid exhibit potential genotoxic and cytotoxic activity against renal cells (Vero …
and cytotoxic effect of Zoledronic acid on renal epithelial cells of monkey and dog kidney, well-…

… zoledronic acid (32 patients had both drugs). Compared with ibandronate, the zoledronic
acid … Zoledronic acid treatment increased the relative risk (RR) and the incidence rate (IR) of …

… kidney disease (CKD) with age-related reductions in glomerular filtration rate (GFR). Intravenous
zoledronic acid is safe … On balance, it appears that the risk of kidney damage in patients …

… Zoledronic acid (ZLD) is a bisphosphonate drug widely administered against pathological
conditions such as hypercalcemia of malignancy, osteoporosis, bone metastases from solid …

… Toxic acute tubular necrosis (ATN) must be differentiated from other forms of drug-induced
toxicity targeting other compartments of the kidney, such as minimal change disease …

… During our own clinical practice, we observed that a subset of OP patients treated with
Zoledronic Acid (ZOL) infusion exhibited elevated creatinine (Cr), decreased estimated …

… of zoledronic acid-related kidney damage was evaluated. For this purpose, the cytotoxic and
antiproliferative effects of zoledronic acid and … in human embryonic kidney (HEK-293) cells. …