Seasonal postembryonic maturation of the diurnal rhythm of serotonin in the chicken pineal gland

A Piesiewicz, U Kedzierska, E Turkowska… - Chronobiology …, 2015 - Taylor & Francis
… in 5-HT content suggested that season- and age-dependent … and used as quantification
standards for qPCR. Transcript … that the urinary excretion of 6-sulfatoxymelatonin (aMT6s) …

Automation and validation of a MALDI-TOF MS (Mass-Fix) replacement of immunofixation electrophoresis in the clinical lab

M Kohlhagen, S Dasari, M Willrich… - Clinical Chemistry and …, 2021 - degruyter.com
… time of flight mass spectrometry (MALDI-TOF MS) method (Mass-Fix) as … Mass-Fix has
demonstrated accurate quantitation in … Detection of M-proteins in urine was also tested in our initial …

Prolonged-release formulation of melatonin (Circadin) for the treatment of insomnia

P Lemoine, N Zisapel - Expert opinion on pharmacotherapy, 2012 - Taylor & Francis
… Melatonin undergoes first-pass hepatic metabolism and > 80% is excreted exclusively in
the urine as 6-sulfatoxymelatonin Citation[53]. Owing to the rapid absorption and short half-life …

A new strategy implementing mass spectrometry in the diagnosis of congenital disorders of N-glycosylation (CDG)

…, R Barone, A Fiumara, MA Donati… - Clinical Chemistry and …, 2021 - degruyter.com
… based on liquid chromatography-mass spectrometry (LC-MS) for the … by mass-spectrometric
measurement. Single TRF isoform … Determination of the mass of the various TRF isoforms is …

Potential of MALDI-TOF mass spectrometry to overcome the interference of hemoglobin variants on HbA1c measurement

A Xu, W Xie, Y Wang, L Ji - Clinical Chemistry and Laboratory …, 2021 - degruyter.com
Objectives Hemoglobin (Hb) variants remain an important cause of erroneous HbA 1c
results. We present an approach to overcome the interference of Hb variants on HbA 1c …

Multi-omics Analysis of Aging Liver Reveals Changes in Endoplasmic Stress and Degradation Pathways in Female Nonhuman Primates

S Puppala, J Chan, KD Zimmerman, Z Hamid… - bioRxiv, 2023 - biorxiv.org
Mass spectrometer data were acquired in MS1 scan mode. All data acquisition was … to
6-sulfatoxymelatonin by aryl sulfotransferase in the liver and subsequently excreted in the urine (…

Measurement uncertainty estimation for derived biological quantities

R Rigo-Bonnin, F Canalias - Clinical Chemistry and Laboratory …, 2021 - degruyter.com
… provide values of derived biological quantities which are calculated from two or more
measured quantities through a functional relationship (eg albumin excretion rate, calculated …

[图书][B] Pharmaceutical, chronobiological and clinical aspects of melatonin

JE Nagtegaal - 2001 - dare.uva.nl
… accounted for by 6-sulfatoxymelatonin in plasma and urine. … are not simply due to an
age-dependent melatonin deficiency. … requiredd to suppress melatonin secretion that may be both …

Prolonged-release melatonin for the treatment of insomnia: targeting quality of sleep and morning alertness

A Wade, N Zisapel, P Lemoine - 2008 - Future Medicine
… The consistently observed age-dependent changes in … have even less 6-sulfatoxymelatonin
(6-SMT) excretion than age-… is excreted exclusively in the urine as 6-sulfatoxymelatonin. …

Metabolomic Markers in Attention-Deficit/Hyperactivity Disorder (ADHD) among Children and Adolescents—A Systematic Review

E Predescu, T Vaidean, AM Rapciuc… - International Journal of …, 2024 - mdpi.com
… specimens from participants, enabling the quantification of … also indicated a high excretion
of 6-sulfatoxymelatonin, another … Furthermore, age-dependent differences were identified …