Polysomnographic study of the effect of melatonin on sleep in elderly patients with chronic primary insomnia

JM Monti, F Alvarino, D Cardinali, I Savio… - Archives of Gerontology …, 1999 - Elsevier
… single-blind, and sleep was recorded and quantified so that the nature and extent of the
sleep … found in one insomniac patient with high urinary 6-sulphatoxymelatonin excretion. …

Artificial Light Pollution at Night: A risk for normal circadian rhythm and physiological functions in humans

P Kumar, MS Ashawat, V Pandit… - Current Environmental …, 2019 - ingentaconnect.com
… disturbance in the nocturnal secretion of melatonin can affect … of urine production and
urinary 6-sulfatoxymelatonin (6SMT), … Further, study and determination of link between light …

Light pollution, circadian photoreception, and melatonin in vertebrates

M Grubisic, A Haim, P Bhusal, DM Dominoni… - Sustainability, 2019 - mdpi.com
… levels of the melatonin metabolite 6-sulfatoxymelatonin (… the normal onset of melatonin
secretion was reported to reduce … Some studies identified age-dependent effects of ALAN. Less …

[PDF][PDF] Light at Night, Human Health-references with abstracts

M Abe, ED Herzog, S Yamazaki, M Straume, H Tei… - wikinight.free.fr
… is wavelength- and/or age-dependent. PERIOD3 (PER3) clock … and/or its metabolite 6sulfatoxymelatonin
(aMT6s) provide … species requires the determination of 24-h secretion profiles. …

[图书][B] Epigenetic Modification in 4T1 Mouse Breast Cancer Model by Artificial Light at Night and Melatonin Treatment: The Role of DNA-Methyltransferase

S Agbaria - 2018 - search.proquest.com
… Table 2: Single Cosine analysis of 6-sulfatoxymelatonin … Notably, disruption of MLT
secretion in mice exposed to … reveals a systemic, age-dependent splenic immune influence …

Mass spectrometric sample identification with indicator compounds introduced via labeled sample tubes

M Paal, K Habler, M Vogeser - Clinical Chemistry and Laboratory …, 2021 - degruyter.com
… We have demonstrated the feasibility of an internal labeling procedure for diagnostic samples
with mass spectrometry-based readout of dissolved indicator compound combinations as …

[PDF][PDF] Role of Oxidative, Nitrative, and Chlorinative Protein Modifications in Aging and Age-Related Diseases

I Sadowska-Bartosz - downloads.hindawi.com
… “scan mode” of the single quadrupole mass spectrometer to determine if the oxysterols were
… of an API 4000 QTrap triple quadrupole mass spectrometer (Applied Biosystems) through a …

Alterations of the Serotonin—IVlelatonin Pathway in Autism Spectrum Disorders: Biological Evidence and Clinical Consequences

C PAGAN, R DELORME, JM LAUNAY… - … : Molecules to Model …, 2012 - books.google.com
… and is excreted in urine. The normal amount of 5-HIAA … by sulfotransferase to form 6-sulfatoxymelatonin
(6-SM), the … similar agedependent pattern, but with significantly higher excretion

Shiftwork and light at night negatively impact molecular and endocrine timekeeping in the female reproductive axis in humans and rodents

AM Yaw, AK McLane-Svoboda… - International Journal of …, 2020 - mdpi.com
… However, more studies are needed to assess how progesterone levels change in … that
indicate nightshifts reduce pregnancy nighttime urine excretion of 6-sulfatoxymelatonin [119]. If …

Sleep-wake as a biological rhythm

P Lavie - Annual review of psychology, 2001 - annualreviews.org
… with the sleep deprivation paradigm to quantify sleepiness, ie … -non-REM cycle are age-dependent.
As described above, the … 5 h of the peak melatonin secretion. Furthermore, exposing …