Pharmacokinetic and pharmacodynamic considerations of general anesthesia in pediatric subjects
… studies investigating circadian rhythm effects on midazolam in children [Citation135] …
pharmacology of drugs used in children. The inability to measure the concentration of intravenous …
pharmacology of drugs used in children. The inability to measure the concentration of intravenous …
[PDF][PDF] T/CMIDAZOLAM INJECTION USP
QC Saint-Hyacinthe - pdf.hres.ca
… and cimetidine or ranitidine had no clinically significant effect on the pharmacokinetics and
pharmacodynamics of midazolam. These data indicate that intravenous midazolam can be …
pharmacodynamics of midazolam. These data indicate that intravenous midazolam can be …
Premedication for endotracheal intubation in the neonate
C McPherson - Neonatal Network, 2018 - connect.springerpub.com
… Because of hypotensive effects in preterm neonates, sedation with midazolam should …
intravenous access, intranasal midazolam allows for provision of sedation. Intranasal midazolam …
intravenous access, intranasal midazolam allows for provision of sedation. Intranasal midazolam …
Pharmacokinetic optimisation of benzodiazepine therapy for acute seizures: focus on delivery routes
E Rey, JM Tréluyer, G Pons - Clinical pharmacokinetics, 1999 - Springer
… and midazolam and their pharmacodynamic effect has been … midazolam. Eleven healthy
volunteers received a single 1-minute intravenous infusion of diazepam 0.15 mg/kg, midazolam …
volunteers received a single 1-minute intravenous infusion of diazepam 0.15 mg/kg, midazolam …
[PDF][PDF] A Comparative study of Oral Midazolam and Oral Melatonin for Premedication in Paediatric Anaesthesia
P Malini - 2020 - repository-tnmgrmu.ac.in
A Dissertation on “ A comparative study of oral midazolam and oral melatonin for premedication
in Paediatric Anaesthesia ” S Page 1 A Dissertation on “ A comparative study of oral …
in Paediatric Anaesthesia ” S Page 1 A Dissertation on “ A comparative study of oral …
Considerations for drug dosing in premature infants
J van den Anker, K Allegaert - … Journal of Clinical Pharmacology, 2021 - Wiley Online Library
… Absorption In the early phase of their critical care, the intravenous route ensures full drug …
for the objective and continuous evaluation of respiration and drug effects in preterm infants. …
for the objective and continuous evaluation of respiration and drug effects in preterm infants. …
Pharmacokinetic/pharmacodynamic modelling to optimize the dose of analgesics and sedatives in children
M Bardol - 2022 - discovery.ucl.ac.uk
… optimal dose of clonidine and midazolam in the PICU (CloSed … an IV dose of 2 µg/kg for
procedural pain in preterm infants. … fentanyl, clonidine and midazolam were defined in specific …
procedural pain in preterm infants. … fentanyl, clonidine and midazolam were defined in specific …
Dose‐linearity of the pharmacokinetics of an intravenous [14C]midazolam microdose in children
BD van Groen, WH Vaes, BK Park… - … pharmacology, 2019 - Wiley Online Library
… In preterm infants, the clearance was reported to be lower (… in preterm infants than in an
infant of 4 kg. A study with critically ill children reported a clearance of 1.11 L h −1 for an infant of …
infant of 4 kg. A study with critically ill children reported a clearance of 1.11 L h −1 for an infant of …
[HTML][HTML] Challenges associated with route of administration in neonatal drug delivery
MW Linakis, JK Roberts, AC Lala, MG Spigarelli… - Clinical …, 2016 - Springer
… in stomach pH are generally not seen in preterm infants who have little free acid during the
… , intranasal midazolam had an onset of action as fast as intravenous midazolam but was …
… , intranasal midazolam had an onset of action as fast as intravenous midazolam but was …
[HTML][HTML] Opioids and alpha-2-agonists for analgesia and sedation in newborn infants: protocol of a systematic review
M Kinoshita, K Stempel, IJB do Nascimento… - Systematic …, 2020 - Springer
… including pharmacokinetics/pharmacodynamics, and … intravenously or orally, and it was
initially used to treat neonatal opioid abstinence [26]. Clonidine reduces fentanyl and midazolam …
initially used to treat neonatal opioid abstinence [26]. Clonidine reduces fentanyl and midazolam …