… in DNA methylation concomitant with altered gene expression patterns in response to 3, 3’,
4, 4’, 5-pentachlorobiphenyl (… We hypothesized that DNA methylation changes play a role in …

… DNA methylation is one of the epigenetic mechanisms that regulates gene expression, …
Our objective was to determine whether the DNA methylation system could be a target following …

… DNA methylation in the testes of mice caused by PCB118 exposure during pregnancy, we
performed immunohistochemistry for 5 … differences in 5 mC relative expressions in both E18.5-…

… 5-meC levels to evaluate the methylation of genomic DNA in the testis of F 1 mice. There were
no significant differences in testicular 5-… In addition, this study found that 5-meC is primarily …

… epigenetic modifications (DNA methylation and chromatin state) and testicular function.
Epidemiological studies have determined an association between dioxin-like PCBs and global …

… 5-pentachlorobiphenyl (PCB 118) exposure on embryo implantation and endometrial receptivity,
with the possible mechanism of DNA methylation … the changes in DNA methylation were …

… To investigate whether the exposure of PCB118 also changed the expression level of genes
that regulate DNA methylation in the testis of offspring, we analyzed the expression levels of …

… The results showed that prenatal exposure to PCB118 altered the DNA methylation status
of differentially methylated regions in some imprinted genes, and the expression levels of …

… the pattern of CpG DNA methylation can play an important role in gene regulation… methylated
genes. We hypothesized that if CpG DNA methylation of the CYP1A1 promoter plays a role …

… The degree of global DNA methylation has been shown to play a role in human health. For
example, DNA hypomethylation was seen in breast cancer cells (Ruike et al., 2010) and in …