… this aberrant DNA methylation “invades” the previously unmethylated CpG island and how
it is maintained through cell divisions. Furthermore, we should remember that this methylation …

… Aberrant DNA methylation is known as an important cause of human cancers, along with
mutations. Although aberrant methylation … alterations: aberrant DNA methylation and mutations. …

… DNA methylation, the addition of a methyl group to the carbon-5 position of cytosine residues,
is the only common covalent modification of human DNA and occurs almost exclusively at …

… aberrant methylation in this growth dysfunction. Global and gene-specific DNA methylation
… Among other epigenetic changes, aberrant DNA methylation might have a great potential as …

… DNA methylation in cancer. … to aberrant DNA methylation. This review will summarize
and discuss current concepts regarding the mechanisms behind aberrant DNA methylation in …

Hypermethylation of CpG islands near gene promoter regions is associated with transcriptional
inactivation and represents an important mechanism of gene silencing in carcinogenesis…

… are DNA methylation and covalent histone modifications (Jones and Baylin 2007). Aberrant
DNA methylation … mucosa, aberrant crypt foci (ACF) (Chan et al. 2002). Promoter CpG island …

… The purpose of this review is to compile recent information on aberrant DNA methylation of …
and to provide insight as to how DNA methylation might serve as targeted treatment option as …

… In summary, recent studies demonstrate that aberrant methylation may be the most common
mechanism of inactivating cancer-related genes in lung cancer, occurs already in smoking-…

… In this study, we use gene array technologies to assess the extent of aberrant DNA methylation
and chromosome aberrations in bone marrow samples from 184 patients with MDS or …