Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

SB Baylin, M Esteller, MR Rountree… - Human molecular …, 2001 - academic.oup.com
genetic alterations, which directly mutate or delete genes, or epigenetic alterations, which
alter the heritable state of gene expression. … chromatin states around gene transcription start …

Aberrant gene expression in humans

Y Zeng, G Wang, E Yang, G Ji… - PLoS …, 2015 - journals.plos.org
genetic variants (ie, eQTL SNPs) show little evidence of involvement. Additional data suggest
that non-genetic factors may also underlie aberrant gene expression. … gene expression

Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile

C Schoch, W Kern, A Kohlmann… - Genes …, 2005 - Wiley Online Library
expression of genes in these regions; (3) a unique gene expression pattern including up-regulation
of genes … AML with a complex aberrant karyotype by gene expression profiling may …

Detection of aberrant gene expression events in RNA sequencing data

VA Yépez, C Mertes, MF Müller, D Klaproth-Andrade… - Nature protocols, 2021 - nature.com
… supporting the detection of aberrant events. Specifically, we provide detailed instructions
to identify aberrant expression, aberrant splicing, and mono-allelic expression (MAE) starting …

Nuclear structure-gene expression interrelationships: implications for aberrant gene expression in cancer

GS Stein, M Montecino, AJ Van Wijnen, JL Stein… - Cancer research, 2000 - AACR
… and aberrant gene expression that occurs during the onset and progression of cancer. A
road map of regulatory events that mediate transcriptional control within the three-dimensional …

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer

A Buness, R Kuner, M Ruschhaupt, A Poustka… - …, 2007 - academic.oup.com
gene expression data to systematically detect patients showing distinct levels of either
consistently higher or lower gene expression in … shows a significantly altered expression level in a …

Variation in gene expression and aberrantly regulated chromosome regions in cloned mice

T Kohda, K Inoue, N Ogonuki, H Miki… - Biology of …, 2005 - academic.oup.com
gene expression pattern of each gene in … genes with similar patterns of varied expression
were clustered. Twenty-one such gene clusters consisting of three or more neighboring genes (…

Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes

L Melchor, E Honrado, MJ Garcia, S Alvarez, J Palacios… - Oncogene, 2008 - nature.com
… between IHC subtypes and specific Genomic Aberration Patterns (GAPs). Our results are very
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical …

Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis

J Guan, E Yang, J Yang, Y Zeng, G Ji, JJ Cai - Human genetics, 2016 - Springer
… To this end, we develop a new gene expression analysis method—aberrant gene … relationship
between gene function and aberrant gene expression, we grouped genes into gene sets, …

[HTML][HTML] Aberrant expression of the PRAC gene in prostate cancer

G Lenka, WH Weng, CK Chuang… - … journal of oncology, 2013 - spandidos-publications.com
… The PRAC gene is known to be commonly expressed in prostate tissue, rectum and colon. …
insights into the expression patterns of PRAC in PCa, we examined the gene expression by …