Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
… While this ability of the cells to maintain such methylation … participate in the abnormal
methylation patterns seen in cancer … produce and maintain DNA methylation patterns in normal …
methylation patterns seen in cancer … produce and maintain DNA methylation patterns in normal …
Aberrant methylation patterns in cancer: a clinical view
A Videtic Paska, P Hudler - Biochemia medica, 2015 - hrcak.srce.hr
… In conclusion, the changes in DNA methylation patterns in tumour cells are slowly gaining
entrance into routine diagnostic tests as promising biomarkers and as potential therapeutic …
entrance into routine diagnostic tests as promising biomarkers and as potential therapeutic …
Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemia
O Galm, S Wilop, C Lüders, E Jost, G Gehbauer… - Annals of …, 2005 - Springer
… Furthermore, the frequency of aberrant p15 methylation increased with disease evolution
towards AML [43]. In our patient cohort, methylation patterns in AML patients with evidence of …
towards AML [43]. In our patient cohort, methylation patterns in AML patients with evidence of …
Aberrant DNA methylation in cancer: potential clinical interventions
G Strathdee, R Brown - Expert reviews in molecular medicine, 2002 - cambridge.org
… DNA methylation might be pivotal in the development of most cancers. In recent years, it has
become apparent that the pattern of DNA methylation … in the levels of DNA methylation, this …
become apparent that the pattern of DNA methylation … in the levels of DNA methylation, this …
Aberrant DNA methylation as a cancer-inducing mechanism
M Esteller - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
… this aberrant DNA methylation “invades” the previously unmethylated CpG island and how
it is maintained through cell divisions. Furthermore, we should remember that this methylation …
it is maintained through cell divisions. Furthermore, we should remember that this methylation …
Aberrant DNA methylation in contrast with mutations
T Ushijima, K Asada - Cancer science, 2010 - Wiley Online Library
… Aberrant DNA methylation is known as an important cause of human cancers, along with
mutations. Although aberrant methylation … alterations: aberrant DNA methylation and mutations. …
mutations. Although aberrant methylation … alterations: aberrant DNA methylation and mutations. …
Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility
RG Urdinguio, GF Bayon, M Dmitrijeva… - Human …, 2015 - academic.oup.com
… , and between DNA hypermethylation and regions … aberrant DNA methylation of sperm in
infertile men could be locus-dependent. Finally, we also show that DNA methylation patterns, …
infertile men could be locus-dependent. Finally, we also show that DNA methylation patterns, …
Origins of aberrant DNA methylation in acute myeloid leukemia
T Schoofs, WE Berdel, C Müller-Tidow - Leukemia, 2014 - nature.com
… DNA methylation in cancer. … to aberrant DNA methylation. This review will summarize
and discuss current concepts regarding the mechanisms behind aberrant DNA methylation in …
and discuss current concepts regarding the mechanisms behind aberrant DNA methylation in …
Aberrant DNA methylation in lung cancer: biological and clinical implications
… In summary, recent studies demonstrate that aberrant methylation may be the most common
mechanism of inactivating cancer-related genes in lung cancer, occurs already in smoking-…
mechanism of inactivating cancer-related genes in lung cancer, occurs already in smoking-…
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
ME Figueroa, L Skrabanek, Y Li… - Blood, The Journal …, 2009 - ashpublications.org
… distribution of DNA methylation of … aberrant DNA methylation involving thousands of genes
than did the normal CD34 + bone marrow cells or de novo AML blasts. Aberrant methylation …
than did the normal CD34 + bone marrow cells or de novo AML blasts. Aberrant methylation …
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