Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

SB Baylin, M Esteller, MR Rountree… - Human molecular …, 2001 - academic.oup.com
… While this ability of the cells to maintain such methylation … participate in the abnormal
methylation patterns seen in cancer … produce and maintain DNA methylation patterns in normal …

Aberrant methylation patterns in cancer: a clinical view

A Videtic Paska, P Hudler - Biochemia medica, 2015 - hrcak.srce.hr
… In conclusion, the changes in DNA methylation patterns in tumour cells are slowly gaining
entrance into routine diagnostic tests as promising biomarkers and as potential therapeutic …

Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemia

O Galm, S Wilop, C Lüders, E Jost, G Gehbauer… - Annals of …, 2005 - Springer
… Furthermore, the frequency of aberrant p15 methylation increased with disease evolution
towards AML [43]. In our patient cohort, methylation patterns in AML patients with evidence of …

Aberrant DNA methylation in cancer: potential clinical interventions

G Strathdee, R Brown - Expert reviews in molecular medicine, 2002 - cambridge.org
DNA methylation might be pivotal in the development of most cancers. In recent years, it has
become apparent that the pattern of DNA methylation … in the levels of DNA methylation, this …

Aberrant DNA methylation as a cancer-inducing mechanism

M Esteller - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
… this aberrant DNA methylation “invades” the previously unmethylated CpG island and how
it is maintained through cell divisions. Furthermore, we should remember that this methylation

Aberrant DNA methylation in contrast with mutations

T Ushijima, K Asada - Cancer science, 2010 - Wiley Online Library
Aberrant DNA methylation is known as an important cause of human cancers, along with
mutations. Although aberrant methylation … alterations: aberrant DNA methylation and mutations. …

Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility

RG Urdinguio, GF Bayon, M Dmitrijeva… - Human …, 2015 - academic.oup.com
… , and between DNA hypermethylation and regions … aberrant DNA methylation of sperm in
infertile men could be locus-dependent. Finally, we also show that DNA methylation patterns, …

Origins of aberrant DNA methylation in acute myeloid leukemia

T Schoofs, WE Berdel, C Müller-Tidow - Leukemia, 2014 - nature.com
DNA methylation in cancer. … to aberrant DNA methylation. This review will summarize
and discuss current concepts regarding the mechanisms behind aberrant DNA methylation in …

Aberrant DNA methylation in lung cancer: biological and clinical implications

S Zöchbauer-Müller, JD Minna, AF Gazdar - The oncologist, 2002 - academic.oup.com
… In summary, recent studies demonstrate that aberrant methylation may be the most common
mechanism of inactivating cancer-related genes in lung cancer, occurs already in smoking-…

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

ME Figueroa, L Skrabanek, Y Li… - Blood, The Journal …, 2009 - ashpublications.org
… distribution of DNA methylation of … aberrant DNA methylation involving thousands of genes
than did the normal CD34 + bone marrow cells or de novo AML blasts. Aberrant methylation