Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome

KN Chitrala, DG Hernandez, MA Nalls, NA Mode… - Epigenetics, 2020 - Taylor & Francis
… The main goal of our study is to examine DNAm signatures measured across the genome
associated with MetS using DNA from urban dwelling AA and White adult participants in the …

[HTML][HTML] Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

SM Tajuddin, DG Hernandez, BH Chen… - Clinical …, 2019 - Springer
African Americans (AAs) experience premature chronic health … methylated CpG positions
(aDMPs) with their effect size in beta values and significance p value in the African American (…

[HTML][HTML] Epigenome-wide association study of prostate cancer in African Americans identifies DNA methylation biomarkers for aggressive disease

Y Xu, CW Tsai, WS Chang, Y Han, M Huang… - Biomolecules, 2021 - mdpi.com
… Leukocyte DNA methylation signatures are excellent … methylation profiling of leukocyte
DNA in African American PCa patients. We observed slightly increased overall DNA methylation

Novel DNA methylation sites associated with cigarette smoking among African Americans

V Barcelona, Y Huang, K Brown, J Liu, W Zhao, M Yu… - Epigenetics, 2019 - Taylor & Francis
… in African American populations. In this study, we investigated the association between
cigarette smoking and DNA methylation (DNAm) among African AmericansAfrican American

[HTML][HTML] Hepatocyte gene expression and DNA methylation as ancestry-dependent mechanisms in African Americans

CS Park, T De, Y Xu, Y Zhong, E Smithberger… - NPJ Genomic …, 2019 - nature.com
African ancestry (WAA). Here we report the correlation of WAA to gene expression and DNA
methylation … We perform mediation analysis to test whether methylation is a mediator of the …

[HTML][HTML] Epigenomic indicators of age in African Americans

JA Smith, AL Zagel, YV Sun, DC Dolinoy… - Hereditary genetics …, 2014 - ncbi.nlm.nih.gov
methylation signatures. Since we assessed a cell population of peripheral blood leukocytes
that consists largely of neutrophils (40–75%) and lymphocytes (16–48%) [48], we recognize …

Racial differences in genome-wide methylation profiling and gene expression in breast tissues from healthy women

MA Song, TM Brasky, C Marian, DY Weng, C Taslim… - Epigenetics, 2015 - Taylor & Francis
Americans (EAs) than in African Americans (AAs) but mortality from breast cancer is higher
among AAs. While there are racial differences in DNA methylation … wide DNA methylation and …

[HTML][HTML] The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women

MV Dogan, B Shields, C Cutrona, L Gao, FX Gibbons… - BMC genomics, 2014 - Springer
African Americanmethylation signature in response to smoking were in the xenobiotic
response pathway regulated by the AHRR gene [11]. In contrast, in this group of African American

DNA methylation provides insight into intergenerational risk for preterm birth in African Americans

SE Parets, KN Conneely, V Kilaru, R Menon… - Epigenetics, 2015 - Taylor & Francis
methylation in leukocytes from African American umbilical cord blood samples and identified
thousands of DNA methylation … the potential for a long-term epigenetic signature of PTB. …

[HTML][HTML] Incorporating local ancestry improves identification of ancestry-associated methylation signatures and meQTLs in African Americans

B Li, BE Aouizerat, Y Cheng, K Anastos… - Communications …, 2022 - nature.com
… We studied DNA methylation and genetic data among African American (AA) and European
American (EA) participants from the VACS (N = 994) and WIHS (N = 230). The VACS …