[HTML][HTML] Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease
…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2020 - Springer
… Data collection and sharing for this project was funded by the Alzheimer's Disease
Neuroimaging Initiative (ADNI) (National Institutes of Health Grant U01 AG024904) and DOD ADNI (…
Neuroimaging Initiative (ADNI) (National Institutes of Health Grant U01 AG024904) and DOD ADNI (…
Epigenetics in Alzheimer's disease: perspective of DNA methylation
… (FAD), and autosomal dominant Alzheimer’s disease (ADAD). Down to the minutest of …
methylation patterns like mitochondrial DNA methylation and ribosomal DNA (rDNA) methylation. …
methylation patterns like mitochondrial DNA methylation and ribosomal DNA (rDNA) methylation. …
[HTML][HTML] DNA methylation: a promising approach in management of Alzheimer's disease and other neurodegenerative disorders
G Kaur, SSS Rathod, MM Ghoneim, S Alshehri… - Biology, 2022 - mdpi.com
… of the disease and detect … association of DNA methylation with the pathogenesis of the
most common neurodegenerative diseases, such as, Alzheimer’s disease, Parkinson’s disease…
most common neurodegenerative diseases, such as, Alzheimer’s disease, Parkinson’s disease…
[HTML][HTML] Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease
… We performed a genome-wide screen of DNA methylation … gyrus of patients with Alzheimer’s
disease and non-demented … Alzheimer’s disease-associated differentially methylated …
disease and non-demented … Alzheimer’s disease-associated differentially methylated …
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
… In stage 1, we carried out a DNA methylation screen for chromosomal regions in which
methylation levels correlate with AD pathology (Online Methods). In stage 2, we replicated the …
methylation levels correlate with AD pathology (Online Methods). In stage 2, we replicated the …
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain
N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… DNA methylation (5-methylcytosine [5mC]) is one of several epigenetic markers altered
in Alzheimer's disease (AD) brain. More recently, attention has been given to DNA …
in Alzheimer's disease (AD) brain. More recently, attention has been given to DNA …
[HTML][HTML] A meta-analysis of brain DNA methylation across sex, age, and Alzheimer's disease points for accelerated epigenetic aging in neurodegeneration
C Pellegrini, C Pirazzini, C Sala, L Sambati… - Frontiers in aging …, 2021 - frontiersin.org
… Alzheimer's disease (AD) is characterized by specific alterations of brain DNA methylation
(… We found that the proportion of sex-dependent probes whose methylation is modified also …
(… We found that the proportion of sex-dependent probes whose methylation is modified also …
[HTML][HTML] DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
KD Siegmund, CM Connor, M Campan, TI Long… - PloS one, 2007 - journals.plos.org
… whether or not DNA methylation is dynamically regulated in … first insight into the dynamics of
DNA methylation in the human … methylation status for these same loci in Alzheimer's disease …
DNA methylation in the human … methylation status for these same loci in Alzheimer's disease …
[HTML][HTML] Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease
… Sinai 15 , London 8 , and Gasparoni 16 methylation studies. To assess the diagnostic
utility of DNA methylation as clinical biomarkers, we also compared methylation differences in …
utility of DNA methylation as clinical biomarkers, we also compared methylation differences in …
[HTML][HTML] Dynamic DNA methylation during aging: a “prophet” of age-related outcomes
FH Xiao, HT Wang, QP Kong - Frontiers in genetics, 2019 - frontiersin.org
… (Δage, DNA methylation age – … -related diseases (eg, Alzheimer’s disease, cardiovascular
disease). In this review, we provide an overview of the dynamic signatures of DNA methylation …
disease). In this review, we provide an overview of the dynamic signatures of DNA methylation …