… DNA methylation is a crucial process in the regulation of gene … aberrant methylated genes
in the pathology of AD based on the machine learning. We first obtained the DNA methylation …

… -related changes in epigenetic DNA modifications, comparing brain tissue from AD patients
and age-matched controls. In addition, we explored DNA methylation in blood samples from …

… , we performed genome-wide DNA methylation sequencing and RNA … , we confirmed their
methylation status and mRNA levels. … DNA methylation sequencing identified a total of 13,777 …

… in DNA methylation marks in Alzheimer's disease, Neurobiology of aging, 45, 30-42 … The
research in this thesis has characterised DNA methylation in post-mortem human AD brains in a …

… Here, we leverage data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test
associations of the leading measures from the 3 generations of DNA methylation algorithms …

… useful approach for epigenomic studies of brain diseases. In addition, our deep-sequencing
DNA methylation maps emphasize the dynamic regulation of enhancer elements in human …

… of Alzheimer’s disease (AD) pathophysiology. Novel approaches using circulating cell-free
DNA (… Methods: We performed DNA methylation profiling of cfDNA from AD patients and …

… developmental periods of global DNA demethylation, their role in the observed methylation
dynamics seems auxiliary and primarily antagonizes the activity of de novo methylation (17, …

… dynamic DNA methylation and demethylation, and the enzymes responsible for methylating
and demethylating DNA, … in postmortem brain tissue from Alzheimer's disease patients, and …

… of DNA methylation meant that genomic methylation profiles … ), indicating that DNA methylation
profiles are dynamic, vary in … Alzheimer's disease (AD) is caused by the gradual decay of …