[HTML][HTML] Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
… Using our own relatively small data set (Table 1), we find no difference between
Alzheimer's disease brains and controls when it comes to epigenetic age acceleration (Supplementary …
Alzheimer's disease brains and controls when it comes to epigenetic age acceleration (Supplementary …
Decreased methylation of the mitochondrial D-loop region in late-onset Alzheimer's disease
A Stoccoro, G Siciliano, L Migliore… - … of Alzheimer's Disease, 2017 - content.iospress.com
… , DNA methylation represents one of the most studied epigenetic modifications in Alzheimer’s
disease (… In the present study, we assessed DNA methylation levels of the mtDNA D-loop …
disease (… In the present study, we assessed DNA methylation levels of the mtDNA D-loop …
[HTML][HTML] DNA methylation biomarkers in aging and age-related diseases
… is the occurrence of dynamic DNA methylation changes in … DNA methylation levels were
also observed in the peripheral blood mononuclear cells of late onset Alzheimer disease …
also observed in the peripheral blood mononuclear cells of late onset Alzheimer disease …
Epigenetics in Alzheimer's disease: a focus on DNA modifications
N Coppieters, M Dragunow - Current pharmaceutical design, 2011 - ingentaconnect.com
… role of epigenetics in the etiology of the disease. In this review we focus on discussing the
roles of DNA methylation and hydroxymethylation in the development and potential treatment …
roles of DNA methylation and hydroxymethylation in the development and potential treatment …
Epigenetic processes in Alzheimer's disease
I Castanho, K Lunnon - Chromatin Signaling and Neurological Disorders, 2019 - Elsevier
… At the epigenomic level, robust changes have been described in both the brain and blood,
with DNA methylation being the most studied epigenetic process to date. Given the recent …
with DNA methylation being the most studied epigenetic process to date. Given the recent …
Epigenetic mechanisms in memory and cognitive decline associated with aging and Alzheimer's disease
… Thus, DNA methylation is a dynamic mechanism employed by the cell to control gene …
DNA methylation status is altered during age-related memory decline and Alzheimer’s disease. …
DNA methylation status is altered during age-related memory decline and Alzheimer’s disease. …
DNA methyltransferases, DNA methylation, and age-associated cognitive function
D Cui, X Xu - International journal of molecular sciences, 2018 - mdpi.com
… on the cytosine DNA methylation process. The DNA methylation process is mediated by
DNA … Alzheimers disease (AD) is one of the most devastating age-related neurodegenerative …
DNA … Alzheimers disease (AD) is one of the most devastating age-related neurodegenerative …
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies
… NIA-Reagan diagnosis of AD (Consensus recommendations for the postmortem diagnosis
of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group …
of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group …
Epigenomics of Alzheimer's disease
R Cacabelos, C Torrellas, F López-Muñoz - Journal of Experimental & …, 2014 - Elsevier
… -wide decrease in DNA methylation.5, 12 The methylation status of repetitive elements (ie, …
contributor of global DNA methylation patterns. The study of global DNA methylation levels for …
contributor of global DNA methylation patterns. The study of global DNA methylation levels for …
[HTML][HTML] Role of TET1-mediated epigenetic modulation in Alzheimer's disease
… In addition to their function as DNA methylation and hydroxymethylation regulators, TET
proteins also function through their direct interaction with other proteins, including transcription …
proteins also function through their direct interaction with other proteins, including transcription …